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Cause of nerve fiber damage in multiple sclerosis identified

Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease.

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Keywords: cause, nerve, fiber, damage, multiple, sclerosis, identified, sclerosi

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Similar news on "Cause of nerve fiber damage in multiple sclerosis identified":

1. Deactivating protein may protect nerve fibers in MS
   04-23-2007 · EurekAlert!
   Oregon Health & Science University neuroscientists are eyeing a protein as a potential therapeutic target for multiple sclerosis because de-activating it protects nerve fibers from damage. OHSU researchers have shown that genetically inactivating a protein called cyclophilin D can protect nerve fibers in a mouse model of multiple sclerosis. Cyclophin D is a key regulator of molecular processes in the nerve cell's powerhouse, the mitochondrion, and can participate in nerve fiber death.
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2. Most important actors in the growth process of neurons identified
   10-11-2006 · EurekAlert!
   Defects in the growth process of our neurons often underlie brain or nerve diseases, such as Alzheimer's disease or multiple sclerosis. Scientists from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the Katholieke Universiteit Leuven, led by Bassem Hassan, have achieved a major step in unraveling the growth process of axons, the offshoots of neurons.
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3. New imaging technique could promote early detection of multiple sclerosis
   06-27-2007 · EurekAlert!
   Researchers from Purdue University have studied and recorded how myelin degrades real-time in live mice using a new imaging technique. Myelin is the fatty sheath coating the axons, or nerve cells, that insulate and aid in efficient nerve fiber conduction. In diseases such as multiple sclerosis, the myelin sheath has been found to degrade.
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4. 'Cars' imaging reveals clues to myelin damage
   06-27-2007 · EurekAlert!
   Researchers have discovered that calcium ions could play a crucial role in multiple sclerosis by activating enzymes that degrade the fatty sheath that insulates nerve fibers.
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5. Calming Factor: DNA vaccine for MS passes initial test
   08-18-2007 · Science News Online
   A DNA vaccine against multiple sclerosis passes a safety trial and shows signs of suppressing immune-directed nerve damage.
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6. Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
   09-20-2007 · EurekAlert!
   Defects on cell-surface sugars may promote the short-term inflammation and long-term neurodegeneration that occurs in the central nervous system of multiple sclerosis patients, according to University of California, Irvine researchers.
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7. Study reveals molecular basis of botulism toxin's deadly activity
   12-14-2006 · EurekAlert!
   Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.
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8. Pregnancy hormone key to repairing nerve cell damage
   02-20-2007 · EurekAlert!
   The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that the pregnancy-related hormone prolactin is responsible for rebuilding the protective coating around nerve cells. New paper to be published in Feb. 21 edition of the Journal of Neuroscience
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9. MS that runs in families appears more severe than non-familial MS
   10-12-2007 · EurekAlert!
   Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.
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10. Scientists identify 'missing link' in process leading to Alzheimer's disease
    02-07-2007 · EurekAlert!
    Scientists at the University of Virginia have identified what appears to be a major missing link in the process that destroys nerve cells in Alzheimer's disease, an incurable disease that slowly destroys memory and cognitive abilities. The findings are reported in the Nov. 20, 2006, issue of the Journal of Cell Biology and could eventually lead to new drugs that target and disrupt specific proteins that conspire in the brain to cause Alzheimer's.
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