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Custom-made cancer cell attacks
02-16-2007 · EurekAlert!Imagine a cancer treatment tailored to the cells in a patient’s body, each person receiving a unique treatment program. This is what Natural Sciences and Engineering Research Council grantee Thomas Ruth and his colleagues hope to accomplish within the next decade. Using the TRIUMF particle accelerator based in Vancouver, British Columbia, they are taking vast amounts of radioactive material and separating the particular atoms they need for therapy
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Keywords: custom-made, cancer, cell, attacks, custom, made, attack
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- Scientists identify switch for brain's natural anti-oxidant defense
10-19-2006 · EurekAlert!
Scientists at Dana-Farber Cancer Institute report they have found how the brain turns on a system designed to protect its nerve cells from toxic "free radicals," a waste product of cell metabolism that has been implicated in some degenerative brain diseases, heart attacks, strokes, cancer and aging.
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- Scientists prove that parts of cell nuclei are not arranged at random
10-19-2006 · EurekAlert!
The nucleus of a mammal cell is made up of component parts arranged in a pattern which can be predicted statistically, says new research published today. Scientists hope this discovery that parts of the inside of a cell nucleus are not arranged at random will give greater insight into how cells work and could eventually lead to a greater understanding of how they become dysfunctional in diseases like cancer.
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- Impaired Gene Helps Nonsmall-cell Lung Cancer Resist Drug
10-02-2006 · ScienceDaily
Lung cancer cells with a defective version of a potential tumor suppressor gene are highly resistant to attack by a platinum-based drug commonly used to treat the disease, researchers at the University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center at Dallas report in the cover article of the Oct. 1 edition of Cancer Research.
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- Pathway to cell death redefined in landmark study
09-20-2007 · EurekAlert!
Researchers from the University of Pittsburgh School of Medicine have determined that an intracellular protein called serpin-6 is crucial to the repair and survival of cell injury. Controlling the process could pave the way to new treatments for cancer, stroke, heart disease, neurological disorders and other killer illnesses. Using a primitive animal model, the scientists also have made cascade of cell death and the role of serpin-6 in saving cells dramatically -- and explosively -- visible.
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- Ireland Cancer Center researchers advance stem cell gene therapy
12-12-2007 · EurekAlert!
Ireland Cancer Center of University Hospitals Case Medical Center researchers recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects. This is the first time selection of this gene has been shown to occur in patients.
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- Synthesis of natural molecule could lead to better anti-cancer drugs
01-23-2008 · EurekAlert!
In early 2007 a marine chemist reported in the Journal of Natural Products that a new natural compound derived from an uncommon deep-sea sponge was extremely effective at inhibiting cancer cell growth. Karl Scheidt, a Northwestern University synthetic chemist, made the molecule in the lab and discovered the reported structure was incorrect. He then determined the real structure of neopeltolide, information that will help researchers learn how the new compound works and possibly lead to new, more-effective anti-cancer drugs.
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- Novel vaccine concept developed by scientists at the Wistar Institute
01-31-2008 · EurekAlert!
A new vaccine design strategy developed by scientists at the Wistar Institute could help to develop vaccines against diseases like AIDS and cervical cancer. The secret is using a herpes simplex protein called glycoprotein D to block a receptor molecule on antigen-presenting cells. Wistar scientists showed that vaccine vectors made by fusing glycoprotein D with genes from HIV and HPV antigens increase the immune system's response to those antigens in cell cultures and mice.
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- First human trial tests stem-cell-based treatment for heart attacks
03-25-2007 · EurekAlert!
Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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- Study analyzes heart attack mortality risk associated with Hodgkin disease treatments
02-06-2007 · EurekAlert!
Doctors have long known that patients treated for Hodgkin disease are at an increased risk for heart attacks. In the February 7 issue of the Journal of the National Cancer Institute, researchers quantify the risk of fatal heart attacks associated with different types of treatment, and they find that the increased risk persists for at least 25 years after Hodgkin disease treatment.
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- New telomere discovery could help explain why cancer cells never stop dividing
10-04-2007 · EurekAlert!
A group working at the Swiss Institute for Experimental Cancer Research in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. This discovery, published online Oct. 4 in Science Express, calls into question our understanding of how telomeres function, and may provide a new avenue of attack for stopping telomere renewal in cancer cells.
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