Daily non-political popular news in brief.

CSHL researchers show RNA splicing factor may be new target for cancer therapy

New results in the field of RNA research establish that the RNA splicing factor SF2/ASF can act as a cancer-causing protein by changing the alternative splicing of other genes critical for growth-control of cells.

Read more »

Keywords: cshl, researchers, show, rna, splicing, factor, target, cancer, therapy, researcher

« Previous | Next »

Similar news on "CSHL researchers show RNA splicing factor may be new target for cancer therapy":

1. RNA splicing factor implicated in ovarian tumor cell growth
   04-09-2007 · EurekAlert!
   An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago.
   Similar news · Read more »
   
2. Researchers show that veins stiffen as we age
   10-31-2006 · EurekAlert!
   As if creaking joints and hardening of the arteries weren't bad enough, a research team from the University of Delaware and the Christiana Care Health System has now confirmed that even our veins stiffen as we age.And that physiological change may be an important factor in the development of high blood pressure, or hypertension, which currently affects an estimated 65 million Americans, most of them older adults, according to UD researcher William Farquhar.
   Similar news · Read more »
   
3. A new target for the treatment of breast cancer
   01-11-2007 · EurekAlert!
   The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Berkeley Lab researchers have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation. TACE is strongly present in a form of breast cancer which responds poorly to current therapies.
   Similar news · Read more »
   
4. T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
   09-18-2007 · EurekAlert!
   Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia, according to researchers at Memorial Sloan-Kettering Cancer Center. By administering repeated doses of T cells designed to express an artificial receptor which recognizes human B cells, the researchers were able to eradicate cancer in 44 percent of mice bearing human ALL tumors.
   Similar news · Read more »
   
5. Team demos safety of RNA therapy
   09-26-2007 · EurekAlert!
   Researchers from MIT, Alnylam Pharmaceuticals and other institutions have demonstrated the safety of a promising type of genetic therapy that could lead to treatments for a wide range of diseases such as cancer.
   Similar news · Read more »
   
6. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients' lives
   11-09-2007 · EurekAlert!
   Chemotherapy given at the same time as radiation therapy can help patients with a certain type of lung cancer live nearly 50 percent longer than they might have otherwise if the same treatment was given differently, according to an international team’s analysis of several trial results.
   Similar news · Read more »
   
7. Src inhibitors may prove beneficial in breast cancer therapy
   07-12-2007 · EurekAlert!
   Estrogen, which binds estrogen receptor alpha (ER-alpha), is a risk factor for breast cancer development. However, one-third of new breast cancers lack detectable ER-alpha. These ER-alpha-negative cancers are more aggressive and have a worse prognosis than do ER-alpha-positive breast cancers, and have been thought to be estrogen independent. In a new JCI study, University of Miami researchers shed further light on the mechanisms regulating ER-alpha expression levels during breast cancer.
   Similar news · Read more »
   
8. Personalized diets may offer relief to advanced cancer patients
   03-09-2007 · EurekAlert!
   Researchers at the University of Alberta studying the effects of chemotherapy and radiation therapy on the senses report that most advanced cancer patients experience unique and persistent taste and smell abnormalities, believed to be a key factor in malnutrition and poor quality of life. Their study suggests that every patient with chemosensory dysfunction has unique symptoms, and a diet tailored to his/her needs would likely improve quality of life.
   Similar news · Read more »
   
9. M. D. Anderson team identifies new oncogene for brain cancer
   07-02-2007 · EurekAlert!
   Research in Proceedings of the National Academy of Sciences transforms biomarker into potential target for therapy. Insulin-like growth factor binding protein 2 is overexpressed in many cancers.
   Similar news · Read more »
   
10. Tumors stopped from spreading to new sites
    04-05-2007 · EurekAlert!
    For several types of cancer, persistently high levels of the soluble factor TGF-beta in the blood after surgery, chemotherapy, or radiation therapy correlate with increased risk of early metastasis and a poor prognosis. Using a mouse model of breast cancer, researchers from Vanderbilt University have now generated evidence to suggest that treatment with TGF-beta inhibitors might help such patients.
    Similar news · Read more »