Daily non-political popular news in brief.
Scientists uncover new target in cancer mutation puzzle
02-18-2007 · EurekAlert!University of Rochester scientists, while investigating the two most frequent types of mutations in cancer, discovered a possible new route to treatment that would take advantage of the mutations instead of trying to repair them. The research is reported online this week in the journal Nature Structural & Molecular Biology.
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Keywords: scientists, uncover, target, cancer, mutation, puzzle, scientist
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- Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
03-21-2007 · EurekAlert!
Scientists have found a gene mutation that can dramatically reduce the number of colon polyps that develop, potentially cutting the risk of cancer. Researchers studying mice prone to develop polyps discovered that animals carrying the damaged gene had about 90 percent fewer polyps in the small intestine and colon. Because people with large numbers of polyps are at higher risk for colon cancer, the finding may provide new ways to diagnose, prevent and treat it.
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- Scientists map key landmarks in human genome
01-16-2007 · EurekAlert!
Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome. The mapping tool could help uncover important clues for understanding and diagnosing cancer and other diseases, the scientists say. Moreover, it may shed light on the role of nucleosomes in the process of "reprogramming" an adult cell to its original embryonic state, which is a critical operation in cloning.
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- Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
04-18-2007 · EurekAlert!
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. Increasingly, stem cells are examined as the cause -- and potential target of treatment -- for many, if not all, cancers.
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- Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
09-23-2007 · EurekAlert!
Italian scientists will announce on Monday (Sept. 24) that they have found a new and promising target for anti-tumor therapy in cancer. Professor Saverio Alberti, from the CESI, University of Chieti Foundation, Chieti, will tell the European Cancer Conference that he and his team have found a widespread mechanism for the stimulation of tumor growth in man, and that this is leading to the development of novel diagnostic and therapeutic procedures.
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- Scientists identify fundamental brain defect, probable drug target in fragile X syndrome
09-17-2007 · EurekAlert!
Scientists have discovered how the gene mutation responsible for fragile X syndrome -- the most common inherited form of mental retardation -- alters the way brain cells communicate. In neurons cultured from laboratory rats, the scientists also were able to reverse the effects of the mutation using a drug targeted to the specific site in an upstream pathway of the defect. The finding could lead to the development of human therapies for this previously untreatable condition.
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- Immune response to cancer stem cells may dictate cancer's course
03-26-2007 · EurekAlert!
Mounting evidence shows that a tumor's growth and spread may depend on "cancer stem cells," which comprise only a very small subset of the tumor. A new study by Rockefeller University scientists shows that immunity to cancer stem cells may help protect people with a precancerous condition from developing the full-blown disease, and that these cells could be an important target for cancer vaccines.
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- Jefferson scientists identify protein key to breast cancer spread, potential new drug target
04-09-2007 · EurekAlert!
Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007, in the journal Proceedings of the National Academy of Sciences, could be a potential target for new drugs aimed at stopping or slowing the growth and progression of breast cancer.
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- Scientists find missing link to understand how plants make vitamin C
04-27-2007 · EurekAlert!
Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery. That is until now. A group of Dartmouth and UCLA researchers, who normally work on genes involved in aging and cancer in animals, discovered the last piece of the puzzle, they report in a study published online April 26 in the Journal of Biological Chemistry.
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- UCF scientists' molecular discovery could help drugs target unhealthy cells
01-18-2007 · EurekAlert!
University of Central Florida and University of California Riverside professors are a step closer to being able to deliver life-saving drugs through tiny molecules that would travel through the bloodstream and destroy only cancer-ridden cells.
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- Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
08-09-2007 · UT Southwestern Medical Center
New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.
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