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Targeting the adrenal gland could be key strategy against heart failure, Jefferson scientists show

02-18-2007 · EurekAlert!

Scientists have staved off heart failure in animals by using gene therapy to shut down the adrenal gland's excessive output of fight or flight hormones such as epinephrine and norepinephrine, which forces the heart to pump too hard. Such a novel approach -- targeting the adrenal gland in addition to the heart -- provides a potential new strategy against heart failure, and could lead to a new class of drugs.

Keywords: targeting, adrenal, gland, key, strategy, heart, failure, jefferson, scientists, show, scientist

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