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RNAi shows promise in gene therapy, Stanford researcher says
02-18-2007 · EurekAlert!Three years ago Mark Kay, MD, PhD, published the first results showing that a biological phenomenon called RNA interference could be an effective gene therapy technique. Since then he has used RNAi gene therapy to effectively shut down the viruses that cause hepatitis and HIV in mice.
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Keywords: rnai, shows, promise, gene, therapy, stanford, researcher, show
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- Signal protein shows promise for blocking tumor promoters in skin cells
11-03-2006 · EurekAlert!
A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells. Using animal models, the researchers discovered that Srcasm acts like a brake in epithelial cells, preventing uncontrolled cell growth caused by a family of proteins called Src kinases. This finding, published online in the Journal of Biological Chemistry, suggests a target for future gene therapy to treat skin, head, neck, colon and breast cancers.
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- Study of drug therapy for compulsive buying yields a puzzle, Stanford researcher says
03-13-2007 · EurekAlert!
Researchers at the Stanford University School of Medicine say they are puzzled by findings from their new study indicating that an antidepressant, which previously showed promise in treating a behavioral disorder known as compulsive buying, did not result in a sustained benefit for the patients who took it.
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- Gene therapy shows promise as treatment for diseased limbs
02-26-2007 · EurekAlert!
New research suggests that gene therapy is a safe treatment method to explore in patients whose lower limbs are at risk for amputation because of poor circulation caused by blocked blood vessels.
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- University of Colorado study shows intensive therapy helps in battle against bipolar disorder
04-02-2007 · EurekAlert!
New results from the largest federally funded bipolar study ever conducted show that patients who receive psychotherapy in addition to medication get better faster from bipolar disorder's debilitating depression and stay better longer, according to a University of Colorado at Boulder researcher involved in the study.
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- Stem cells show promise for treating Huntington's disease
09-25-2007 · EurekAlert!
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease. Scientists used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s, generating new medium spiny neurons -- the cell lost in Huntington's disease.
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- Gene therapy for erectile dysfunction shows promise in clinical trial
12-01-2006 · EurekAlert!
The first human trial of gene transfer therapy for erectile dysfunction (ED) indicates that gene therapy that lasts for months and eliminates the patient's need for on-demand drugs (such as Viagra and Cialis), could become the future treatment of choice for this common problem, according to a paper in the most recent issue of Human Gene Therapy.
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- PET scans show gene therapy normalizes brain function in Parkinson's patients
11-19-2007 · EurekAlert!
Experimental gene therapy, brain function effects are present a year later.
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- Study finds lapatinib shows promise as therapy for inflammatory breast cancer
12-14-2006 · EurekAlert!
In the first multi-center clinical trial conducted to better understand the complexities of a rare, aggressive and often lethal form of breast cancer, researchers have discovered that the experimental biological agent, lapatinib, successfully and specifically treats inflammatory breast cancer (IBC).
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- Batten down the hatches against HIV
02-20-2007 · EurekAlert!
A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein. A stumbling block has been the efficient and targeted delivery of RNA into the cells. Researchers led by Hongjie Dai at Stanford University have sucessfully used carbon nanotubes as a "means of transport," they write in "Angewandte Chemie."
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- Gene's activity points to more lethal subtype of AML
07-09-2007 · EurekAlert!
A new study shows that the activity of a particular gene can identify people who have a more lethal form of acute myeloid leukemia, singling out those patients who should receive more intense therapy. The gene, called ERG (for ETS-related gene), has also been linked to chronic leukemia and to breast and prostate cancer.
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