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Mouse stem cell line advance suggests potential for IVF-incompetent eggs
02-19-2007 · EurekAlert!Researchers have found that mouse oocytes that fail to become fertilized during in vitro fertilization are nevertheless often capable of succeeding as "cytoplasmic donors" during a subsequent cloning step using so-called nuclear transfer. Although the implications for human eggs are not yet clear, the findings are of interest because of the ethical and practical concerns surrounding the need for fresh human oocytes for similar nuclear-transfer procedures using human cells.
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Keywords: mouse, stem, cell, line, advance, suggests, potential, ivf-incompetent, eggs, suggest, ivf, incompetent, egg
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- Clinical data suggest potential versatility of ALIMTA-based regimens in lung cancer
06-02-2007 · EurekAlert!
ALIMTA (pemetrexed for injection) showed additional utility in the treatment of the most diagnosed type of cancer, according to data presented today at the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO). Results from a Phase III study suggest that a first-line ALIMTA-based regimen may deliver less toxicity than a commonly used therapy in advanced non-small cell lung cancer (NSCLC). ALIMTA is manufactured and marketed by Eli Lilly and Company.
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- Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
08-02-2007 · EurekAlert!
Can a genetic signature identify the origin of a human stem cell line? Scientists report that a widely available method for comprehensive genetic analysis can help distinguish the type of human embryo that stem cells come from.
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- Reprogrammed human adult stem cells rescue diseased muscle in mice
12-12-2007 · EurekAlert!
Scientists report that adult stem cells isolated from humans with muscular dystrophy can be genetically corrected and used to induce functional improvement when transplanted into a mouse model of the disease. The research, published by Cell Press in the December issue of Cell Stem Cell, represents a significant advance toward the future development of a gene therapy that uses a patient's own cells to treat this devastating muscle-wasting disease.
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- Stroke victims may benefit from stem cell transplants
01-28-2008 · EurekAlert!
Two studies published in the current issue of Cell Transplantation examine the potential for cell transplants to benefit stroke victims. When injected into animal models and tracked via chemical tags and imaging, mensenchymal stem cells in one study, and bone marrow stromal cells in a second study, migrated within one to two weeks to affected brain areas and became therapeutically active. Both studies suggest that novel stem cell therapies can be developed.
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- Fat stem cells being studied as option for breast reconstruction
10-26-2006 · EurekAlert!
Breast cancer survivors might one day avoid the prospect of invasive breast reconstruction surgery, opting instead for an approach that would involve using stem cells from their own fat, suggest researchers who are studying the potential these cells may have for regenerating new breast tissue. In animal models, they hope to prove that an injection of fat stem cells that are seeded onto microscopic scaffold structures will enable production of durable, replacement soft tissue.
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- Cancer stem cells can go it alone
06-11-2007 · EurekAlert!
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line -- established long ago -- turned out to behave a lot like cancer stem cells.
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- Forsyth scientists gain new understanding of adult stem cell regulation
08-01-2007 · EurekAlert!
Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells. Research with the flatworm, planaria, found a novel role for the proteins involved in cell-to-cell communication. This work has the potential to help scientists understand the nature of the messages that control stem cell regulation -- such as the message that maintain and tells a stem cell to specialize and to become part of an organ (e.g., liver or skin).
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- Study reveals how stem cells decide to become either skeletal or smooth muscle
10-10-2007 · EurekAlert!
Researchers have discovered that a key protein controls how stem cells 'choose' to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels. The results suggest new ways to treat atherosclerosis and cancer, diseases that involve the creation of new blood vessels from stem cell reserves that would otherwise replace worn out skeletal muscle.
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- Studies attribute recent increase in multiple myeloma survival to novel therapies
11-01-2007 · EurekAlert!
Multiple myeloma is one of the most common and devastating bone marrow cancers in the US, but survival rates have risen dramatically over the past decade. Recent analyses suggest that this trend may be attributed to new types of drugs and aggressive therapeutic interventions such as stem cell transplantation, according to the results of two studies prepublished online in Blood, the official journal of the American Society of Hematology.
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- Semen ingredient 'drastically' enhances HIV infection
12-13-2007 · EurekAlert!
A plentiful ingredient found in human semen drastically enhances the ability of the human immunodeficiency virus (HIV) to cause infection, according to a report in the Dec. 14, 2007, issue of the journal Cell, a publication of Cell Press. The findings help to understand the sexual transmission of HIV and suggest a potential new target for preventing the spread of AIDS, the researchers said.
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