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Smoking produces changes in human brain like those in animals using illicit drugs
02-20-2007 · EurekAlert!New research shows for the first time that smoking produces long-lasting biochemical changes in the human brain similar to those changes previously seen in the brains of animals that used cocaine, heroin, and other illicit drugs.
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Keywords: smoking, produces, changes, human, brain, animals, illicit, drugs, produce, change, animal, drug
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- Study found no drug interference with pomegranate juice
08-20-2007 · EurekAlert!
A study published in the Journal of Clinical Pharmacology finds that pomegranate juice does not interact with medication. Earlier studies suggested that, like grapefruit juice, pomegranate juice may interfere with metabolism of drugs by inhibiting CYP3A, an enzyme that allows the body to transform and eliminate a drug. This is the first study using human subjects to test the drug interactions of pomegranate juice, unlike prior studies which were conducted in vitro and in animals.
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- UC Davis researchers discover key to body's ability to detect subtle temperature changes
02-26-2007 · EurekAlert!
Scientists have long known the molecular mechanisms behind most of the body's sensing capabilities. Vision, for example, is made possible in part by rhodopsin, a pigment molecule that is extremely sensitive to light. It is involved in turning photons into electrical signals that can be decoded by the brain into visual information. But how the human body is able to sense a one-degree change in temperature has remained a mystery.
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- National Academy of Sciences highlights UCSB study on visual attention
09-24-2007 · EurekAlert!
Now a team of researchers at the University of California, Santa Barbara has identified a nonconscious attention system, which still exists in the human brain, that maintains awareness of nonhuman animals and tracks changes in their location, behavior and trajectory.
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- One shot of gene therapy spreads through brain in animal study
10-08-2007 · EurekAlert!
By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain—after one injection of gene therapy. If these results in animals can be realized in people, researchers may have a potential method for gene therapy to treat a host of rare but devastating congenital human neurological disorders, such as Tay-Sachs disease.
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- Epilepsy-induced brain cell damage prevented in the laboratory
10-29-2007 · EurekAlert!
For some epilepsy patients, the condition's side effects can be as troubling as the seizures. One pressing concern is potential cognitive impairment from seizures, which can include memory loss, slowed reactions and reduced attention spans. Now researchers have linked such cognitive impairments to structural changes in brain cells caused by seizures. They report that the insights they gained allowed them to use a drug to block those changes in the brains of laboratory animals.
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- Brain circuitry that drives drug-seeking compulsion identified
02-06-2008 · EurekAlert!
In experiments with rats, researchers have identified the change in brain circuitry that drives development of a compulsion to seek drugs, even when that compulsion is self-destructive...
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- The human brain: Detective of auditory and visual change
01-18-2008 · EurekAlert!
The human brain is capable of detecting the slightest visual and auditory changes. Several studies have indicated, however, that even a small span of time in between pre- and post-change images can disturb the brain's ability to detect visual discrepancies. In a recent study, psychologists assessed the effect of time gaps on change detection in audition.
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- Complexity constrains evolution of human brain genes
12-25-2006 · EurekAlert!
Despite the explosive growth in size and complexity of the human brain, the pace of evolutionary change among the thousands of genes expressed in brain tissue has actually slowed since the split, millions of years ago, between human and chimpanzee.
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- New finding points way to foiling anthrax's tricks
11-30-2006 · EurekAlert!
Anthrax, when inhaled, is nearly always fatal, in part because the bacteria have a very effective way of stealing iron from human cells to reproduce. This involves two molecules, siderophores, that compete with the body's own iron-transport molecules. UC Berkeley researchers have now found that humans produce a protein that sidelines one of these siderophores, but not the other. A drug that blocks the second siderophore should be able to stop anthrax in its tracks.
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- Protein inhibitor tangles with Alzheimer's disease
02-15-2007 · EurekAlert!
A hallmark of Alzheimer's disease (AD) is the abnormal accumulation of phosphorylated forms of a protein known as tau. In a new study, Mayo Clinic researchers have now shown in mice that a drug that inhibits the function of the protein Hsp90 (EC102) reduces the amount of phosphorylated tau in the brain. Unlike many drugs, EC102 is able to cross the blood-brain barrier, making it a highly promising therapeutic candidate for AD.
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