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Protein important in blood clotting may also play a role in fertility
10-19-2006 · EurekAlert!A protein known to play a role in blood clotting and other cell functions is also critical for proper sperm formation in mice, according to researchers from the University of North Carolina at Chapel Hill School of Medicine.
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Keywords: protein, important, blood, clotting, play, role, fertility
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- Blood clotting protein linked to rheumatoid arthritis
11-16-2007 · EurekAlert!
Researchers at Cincinnati Children's have issued the first study showing that a protein involved in blood clotting (fibrin), also plays an important role in the development of rheumatoid arthritis. Inflammatory joint disease appears to be driven by the engagement of inflammatory cells with fibrin matrices through a specific integrin receptor, aMD2. Researchers suggest that therapies designed to interrupt the localized interaction of inflammatory cells and fibrin may help arthritis patients.
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- RNA-binding protein key to understanding myotonic dystrophy type 1
10-11-2007 · EurekAlert!
Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears today in the journal Molecular Cell.
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- Protein controls blood vessel formation, offers new drug target
12-04-2007 · EurekAlert!
A protein called CIB1 discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine appears to play a major role in controlling new blood vessel growth, offering a target for drug treatments to help the body repair itself after injury and control unwanted blood vessel growth.
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- Joslin study indicates insulin receptors play a critical role in promoting islet growth
04-02-2007 · EurekAlert!
A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.
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- Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread
01-10-2008 · EurekAlert!
A protein that helps prevent a woman's body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers found that the metastatic pancreatic cancer cells in the lymph nodes produce enough of the protein, IDO, to wall-off the immune system's T-cells and recruit cells that suppress the immune response to the tumor.
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- JCI table of contents -- March 22, 2007
03-22-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, March 22, 2007, in the JCI, including: New protein implicated in autism; Prenatal exposure to glucocorticoids has long-term deleterious effects on newborns; Leukemic cells find protection from anticancer drug in the bone marrow; Inflammatory pathway leads to Duchenne muscular dystrophy; Protein’s role in blood clotting differs in vitro and in vivo; and Disease-causing genetic mutation reveals its molecular secrets.
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- Yale discovery suggests protein may play a role in severe asthma
11-14-2007 · EurekAlert!
A protein measured in a simple blood test may be a new biomarker to identify patients with the most serious form of asthma.
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- JCI table of contents: Nov. 21, 2007
11-21-2007 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Nov. 21, 2007, in the JCI, including: Pregnant women pass on the effects of smoking; Location, location, location: gene determining body organ position identified; New role for intestinal protein in blood clotting; Two hits are better than one for causing leukemia; Diabetic hearts feel the burn; and others.
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- New class of RNA molecules may be important in human cancer
09-11-2007 · EurekAlert!
New research shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved noncoding RNAs have been considered "junk" by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
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- Researchers identify a role for glucose-sensing neurons in type 2 diabetes
08-29-2007 · EurekAlert!
In cases of Type 2 diabetes, the body's cells fail to appropriately regulate blood glucose levels. Research led by scientists at Beth Israel Deaconess Medical Center and Oregon Health & Science University describes a previously unrecognized role for glucose-sensing neurons in the onset of the disease demonstrating that an important component of Type 2 diabetes may indeed be "in your head."
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