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Gene therapy shows promise as treatment for diseased limbs
02-26-2007 · EurekAlert!New research suggests that gene therapy is a safe treatment method to explore in patients whose lower limbs are at risk for amputation because of poor circulation caused by blocked blood vessels.
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Keywords: gene, therapy, shows, promise, treatment, diseased, limbs, show, limb
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- Stem cells show promise for treating Huntington's disease
09-25-2007 · EurekAlert!
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease. Scientists used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s, generating new medium spiny neurons -- the cell lost in Huntington's disease.
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- Gene therapy for erectile dysfunction shows promise in clinical trial
12-01-2006 · EurekAlert!
The first human trial of gene transfer therapy for erectile dysfunction (ED) indicates that gene therapy that lasts for months and eliminates the patient's need for on-demand drugs (such as Viagra and Cialis), could become the future treatment of choice for this common problem, according to a paper in the most recent issue of Human Gene Therapy.
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- Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
09-23-2007 · EurekAlert!
Italian scientists will announce on Monday (Sept. 24) that they have found a new and promising target for anti-tumor therapy in cancer. Professor Saverio Alberti, from the CESI, University of Chieti Foundation, Chieti, will tell the European Cancer Conference that he and his team have found a widespread mechanism for the stimulation of tumor growth in man, and that this is leading to the development of novel diagnostic and therapeutic procedures.
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- Novel MS drug shows promise in 2 lethal leukemias
08-28-2007 · EurekAlert!
A new study suggests that an experimental drug being tested for the treatment of multiple sclerosis and to prevent organ rejection might also help people with certain deadly forms of chronic and acute leukemia. The laboratory and animal study focused on the drug, called fingolimod. Researchers said it might help patients with advanced chronic myelogenous leukemia or acute lymphocytic leukemia, and whose cancer cells show a particular genetic change called the Philadelphia chromosome.
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- Gene therapy a possibility for metachromatic leukodystrophy?
11-01-2006 · EurekAlert!
There are currently no therapies for metachromatic leukodystrophy, which causes progressively more severe neurological defects that result in death early in life. Individuals with MLD lack the protein ARSA. A new study shows that the neurological defects in mice lacking ARSA can be corrected by treatment with hematopoietic stem progenitor cells genetically modified to express ARSA, leading to the suggestion that HSPC gene therapy might be efficacious for the treatment of MLD.
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- Cancer researchers add spice to research against rare neuromuscular disease
03-20-2007 · EurekAlert!
Scientists have discovered a compound that shows promise against a debilitating neurodegenerative condition known as Kennedy's disease, which is caused by a mutant gene. Currently there is no treatment for the inherited disorder, which resembles a slowly progressive form of Lou Gehrig's disease and affects mainly men.
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- RNAi shows promise in gene therapy, Stanford researcher says
02-18-2007 · EurekAlert!
Three years ago Mark Kay, MD, PhD, published the first results showing that a biological phenomenon called RNA interference could be an effective gene therapy technique. Since then he has used RNAi gene therapy to effectively shut down the viruses that cause hepatitis and HIV in mice.
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- Study shows interruption of antiretroviral therapy increases risk of disease and death
11-30-2006 · EurekAlert!
Findings from one of the largest HIV/AIDS therapy studies show that a specific strategy of interrupting antiretroviral therapy more than doubles the risk of AIDS or death from any cause. Researchers affiliated with the Mailman School of Public Health led a large multi-center international study, known as Strategies for Management of Anti-Retroviral Therapies, or SMART, comparing two treatment strategies for people with human immunodeficiency virus. Findings demonstrate the value of continuous antiretroviral therapy.
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- Gene therapy, cancer-killing viruses and new drugs highlight novel approaches to cancer treatment
04-17-2007 · EurekAlert!
Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.
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- Signal protein shows promise for blocking tumor promoters in skin cells
11-03-2006 · EurekAlert!
A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells. Using animal models, the researchers discovered that Srcasm acts like a brake in epithelial cells, preventing uncontrolled cell growth caused by a family of proteins called Src kinases. This finding, published online in the Journal of Biological Chemistry, suggests a target for future gene therapy to treat skin, head, neck, colon and breast cancers.
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