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Sox17 required for steps from embryonic to heart muscle cell
02-26-2007 · EurekAlert!The gene Sox17 is discovered to play a central role in the complicated dance of signals, enzymes and proteins that transform embryonic stem cells into a beating heart muscle cell.
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Keywords: sox17, required, steps, embryonic, heart, muscle, cell, step
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Similar news on "Sox17 required for steps from embryonic to heart muscle cell":
- Mass. General researchers identify master cardiac stem cell
11-22-2006 · EurekAlert!
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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- Researchers safely regenerate failing mouse hearts with programmed embryonic stem cells
02-27-2007 · EurekAlert!
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor -- which, so far, has impeded successful translation into practice of embryonic stem cell research.
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- An ambulance man for muscle damage
12-18-2007 · EurekAlert!
Researchers of the European Molecular Biology Laboratory's Mouse Biology Unit, Italy, and the Harefield Heart Science Centre of Imperial College London, have now discovered a molecular signal that helps muscle regenerate and protects it from atrophy. In this week's issue of the Journal of Cell Biology they report that the naturally occurring protein is a promising candidate for new strategies in treating muscle damage and wasting.
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- Discovery of cardiac stem cells may advance regenerative heart therapy
11-22-2006 · EurekAlert!
An immediate early publication of the journal Cell, published by Cell Press, on Nov. 22, 2006, points to the possible existence of master cardiac stem cells with the capacity to produce all three major tissues of the mammalian heart. A companion Cell paper also published online reports the discovery of a second population of cardiac progenitors, which are capable of forming both cardiac muscle and the smooth muscle found in the heart's blood vessel walls.
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- Scientists overcome obstacles to stem cell heart repair
12-12-2007 · EurekAlert!
Scientists have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts. Presenting the research at a UK Stem Cell Initiative conference the researchers will explain how they have made significant progress in maturing beating heart cells derived from embryonic stem cells and in developing the physical scaffolding that would be needed to hold the patch in place in the heart in any future clinical application.
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- Weizmann Institute scientists discover a key player in embryonic muscle development
04-11-2007 · EurekAlert!
In the final stage of muscle fiber development, the cell membranes of attached myoblasts open up and fuse together, forming one large, unified cell. It is known how myoblasts identify other myoblasts and cling together, but the way that the cell membranes fuse into one has remained a mystery. Scientists have now discovered that a protein called WIP plays a key role in muscle cell fusion.
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- Human derived stem cells can repair rat hearts damaged by heart attack
08-26-2007 · EurekAlert!
When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology. The researchers also developed a new process that greatly improves how stem cells are turned into heart muscle cells and then survive after being implanted in the damaged rat heart.
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- Chemical cues turn embryonic stem cells into cerebellar neurons
03-14-2007 · EurekAlert!
Rockefeller University scientists show that embryonic stem cells implanted in the brain appear to develop into fully differentiated granule neurons, the most plentiful neuron in the cerebellum. The findings are a step toward understanding how embryonic stem cells could be regulated in vivo and ultimately used for cell replacement therapy, especially after childhood tumors, in the central nervous system.
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- Muscle stem cells may offer a new treatment option for congestive heart failure
03-25-2007 · EurekAlert!
As a new wave of stem cell research continues, cardiologists are trying to tap into the self-renewing cells' life-saving potential. Scientists have performed the first US controlled, randomized Phase I clinical trial using a three-dimensional guided catheter system to deliver muscular stem cells to the heart. The study was presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit in New Orleans.
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- Simple recipe turns human skin cells into embryonic stem cell-like cells
11-20-2007 · EurekAlert!
A simple recipe -- including just four ingredients -- can transform adult human skin cells into cells that resemble embryonic stem cells, researchers report in an immediate early publication of the journal Cell, a publication of Cell Press. The converted cells have many of the physical, growth and genetic features typically found in embryonic stem cells and can differentiate to produce other tissue types, including neurons and heart tissue, according to the researchers.
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