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Biodegradable microspheres deliver time release vaccines, stimulate different immune response
02-28-2007 · EurekAlert!A new vaccine delivery system using microspheres of a biodegradable polymer may not only reduce the need for booster shots in some cases, but also appears to stimulate an immune response that traditional vaccines do not. Researchers from Iowa State University report their findings today at the ASM Biodefense and Emerging Disease Research Meeting.
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Keywords: biodegradable, microspheres, deliver, time, release, vaccines, stimulate, different, immune, response, microsphere, vaccine
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11-15-2007 · EurekAlert!
Leading efforts to create an HIV vaccine have hinged on the use of viruses as carriers for selected elements of the HIV virus. Recently, however, evidence has emerged that some of these so-called viral vector systems may undermine the immune system and should not be used for vaccine development. Now, a new study from scientists at the Wistar Institute provides strong support for the idea that some viral-vector vaccines may cause more harm than good.
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- Chronic HIV-1 infection frequently fails to protect against superinfection
11-15-2007 · EurekAlert!
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01-31-2008 · EurekAlert!
A new vaccine design strategy developed by scientists at the Wistar Institute could help to develop vaccines against diseases like AIDS and cervical cancer. The secret is using a herpes simplex protein called glycoprotein D to block a receptor molecule on antigen-presenting cells. Wistar scientists showed that vaccine vectors made by fusing glycoprotein D with genes from HIV and HPV antigens increase the immune system's response to those antigens in cell cultures and mice.
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- Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?
04-30-2007 · EurekAlert!
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- New target for HIV/AIDS drugs and vaccine discovered
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