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Making daughters different -- How immune cells take divergent paths when fighting infections
03-01-2007 · EurekAlert!How do immune cells decide to respond to invading microbes by either fighting to the death or becoming the body's memory for future infections? Researchers at the University of Pennsylvania School of Medicine have discovered that immune cells can differ in their inheritance of molecules that regulate cell fate, and therefore what role they play in fighting infection.
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01-31-2008 · EurekAlert!
University of Minnesota researchers have discovered a new way to turn genes off in human T cells, a type of white blood cell that helps the immune system fight infections.Turning off genes, through a process known as mRNA decay, is important for regulating the body's immune response after fighting infection. This research could lead to development of new drugs that turn off the immune system in patients with autoimmune diseases -- such as rheumatoid arthritis and lupus.
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- Immune cells fighting chronic infections become progressively 'exhausted,' ineffective
10-18-2007 · EurekAlert!
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- Penn researchers discover new molecular path to fight autoimmune diseases
03-06-2007 · EurekAlert!
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12-14-2006 · EurekAlert!
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- Chronic infection persists by targeting stromal cell network in lymphoid organs
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