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Treating male infertility with stem cells
03-01-2007 · EurekAlert!New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the March issue of The American Journal of Pathology.
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Keywords: treating, male, infertility, stem, cells, cell
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- Stem cells show promise for treating Huntington's disease
09-25-2007 · EurekAlert!
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease. Scientists used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s, generating new medium spiny neurons -- the cell lost in Huntington's disease.
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- MicroRNA regulates cancer stem cells
12-13-2007 · EurekAlert!
Researchers have discovered a key molecular switch that regulates cancer stem cells. This switch, which belongs to a class of molecules called microRNAs, can decrease a cancer stem cell's ability to propagate tumors. These findings offer a way for targeting cancer stem cells directly, and as a result open up new avenues for potentially treating cancer as a whole.
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- Adult stem cell application effective in treatment of peripheric vascular disease
01-24-2008 · EurekAlert!
Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Discovery of cardiac stem cells may advance regenerative heart therapy
11-22-2006 · EurekAlert!
An immediate early publication of the journal Cell, published by Cell Press, on Nov. 22, 2006, points to the possible existence of master cardiac stem cells with the capacity to produce all three major tissues of the mammalian heart. A companion Cell paper also published online reports the discovery of a second population of cardiac progenitors, which are capable of forming both cardiac muscle and the smooth muscle found in the heart's blood vessel walls.
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- Neural stem cells lend the brain a surprising capacity for self-repair
12-14-2006 · EurekAlert!
The brain contains stem cells with a surprising capacity for repair, researchers report in the Dec. 15 issue of the journal Cell, published by Cell Press. The novel insight into the brain's natural ability to heal might ultimately have clinical implications for the treatment of brain damage, according to the researchers.
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- Loss of stem cells correlates with premature aging in animal study
06-06-2007 · EurekAlert!
Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
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- A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
07-19-2007 · EurekAlert!
A new method of adult stem cell growth, designed in the Area of Cellular Therapy of the University Clinic (University of Navarra), has demonstrated its efficacy for its capacity to grow cornea stem cells.
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- Scientists find stem cell switch
07-26-2007 · EurekAlert!
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth. Poor soil structure is a problem in tropical agriculture, where soil becomes compact as it dries out. Professor Liam Dolan, of the John Innes Centre in Norwich, UK and his team determined that the plant hormone ethylene regulates cell division in root stem cells.
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