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Fixes for Fatty Liver

03-03-2007 · Science News Online

A slate of experimental treatments, including three established diabetes drugs, could become medicines for nonalcoholic fatty liver disease, an obesity-related cause of cirrhosis.

Keywords: fixes, fatty, liver, fixe

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Researchers Estimate Significant Fatty Liver Disease In Children
10-02-2006 · ScienceDaily
Until now little was known about the prevalence of non-alcoholic fatty liver disease (NAFLD) in children. To gauge its occurrence a University of California, San Diego (UCSD) School of Medicine-led team studied 742 autopsy reports and tissue analysis of San Diego County children aged two to 19 who died from traumatic accidents, homicide or suicide and had a medical examiner autopsy between 1993 and 2003.
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Incidence of Fatty Liver Disease rises as obesity in children increases
03-15-2007 · EurekAlert!
As part of a national multicenter research network, Indiana University School of Medicine researchers are looking at Vitamin E and at metformin, a drug used to treat Type II diabetes, as possible therapies for Fatty Liver Disease in 8 to 17 year olds. Fatty Liver Disease may exist in 15 percent or more of obese children.
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Study identifies new regulator of fat metabolism
06-05-2007 · EurekAlert!
Over the past several years, animal studies have shown that high-fat, low-carbohydrate "ketogenic" diets cause demonstrable changes in metabolism and subsequent weight loss. Now, researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a key mechanism behind this turn of events. Their findings, which appear in the June 2007 issue of Cell Metabolism, demonstrate that a liver hormone known as FGF21 is required to oxidize fatty acids -- and thereby burn calories.
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Attenuation of NASH by stimulation of free fatty acid metabolism
10-26-2007 · EurekAlert!
The prevalence of obesity around the world is booming. Consequently, obesity-associated comorbid diseases, such as non-alcoholic steatohepatitis are also escalating. NASH can progress to cirrhosis and the need for liver transplantation. Thus, many researchers have sought ways to reduce the occurrence of NASH. Recent work from the Mayo Clinic has been promising. Dr. Baskin-Bey and colleagues have ameliorated steatosis, liver inflammation and injury in an animal model of NASH by the induction of key enzymes of fatty acid oxidation.
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A simple new way to predict advanced fibrosis in patients with nonalcoholic fatty liver disease
04-02-2007 · EurekAlert!
Certain routine demographic, clinical, and laboratory values can be used to identify advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). This method could render liver biopsy unnecessary in a large proportion of patients.
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Geisinger launches extensive study on obesity and related liver problem
04-16-2007 · EurekAlert!
Geisinger Health System researchers in Danville, Pa., are looking at the genetics of obesity through a unique study. Geisinger patients have voluntarily donated more than 600 liver tissue samples so that researchers can study obesity and also develop a safer, noninvasive way of detecting an obesity-related condition: nonalcoholic fatty liver disease. Relying on several core system resources in the study, Geisinger researchers hope to know more about nonalcoholic fatty liver disease and related health problems.
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Researchers show that fibrosis can be stopped, cured and reversed
12-26-2007 · EurekAlert!
University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed. Their discovery, to be published in PLoS Online on Dec. 26, opens the door to treating and curing conditions that lead to excessive tissue scarring such as viral hepatitis, fatty liver disease, cirrhosis, pulmonary fibrosis, scleroderma and burns.
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New techniques redefine assessment of liver disease
05-20-2007 · EurekAlert!
Research presented today at Digestive Disease Week 2007 introduces unique methods for evaluating patients with non-alcoholic fatty liver disease. NAFLD is the most common liver disease in the world and the development of novel procedures for definitively diagnosing the disease and assessing its prognosis is extremely important for tailoring effective treatments. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
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Quick-burning carbs may cause fatty liver
09-20-2007 · EurekAlert!
The obesity epidemic has spawned not just diabetes, but another serious public health problem: a surge in fatty liver disease, which can lead to cirrhosis and liver failure. Now, research suggests that limiting consumption of high-glycemic-index carbohydrates can prevent the condition in mice. A clinical trial is now testing this idea in overweight adolescents, as well as the possibility of reversing fatty liver disease through diet.
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'Supersize me' mice research offers grim warning for America's fast food consumers
05-23-2007 · EurekAlert!
New Saint Louis University research presented this week found fatty liver disease and signs of type 2 diabetes after only four weeks of a high-fat, high-sugar diet.
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