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How antipsychotic drugs can cause weight gain
03-03-2007 · Science News OnlineA study of mice has identified a biological mechanism by which medications called atypical antipsychotics cause people to gain weight.
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Keywords: antipsychotic, drugs, cause, weight, gain, drug
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- Hopkins scientists uncover cause of antipsychotic drug weight gain
02-12-2007 · EurekAlert!
Johns Hopkins brain scientists have hit on how and why some powerful drugs used for treating mental illnesses cause patients to gain so much weight that they often develop life-threatening complications such as diabetes and heart disease.
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- Diabetes medication and lifestyle changes can help treat weight gain induced by antipsychotic drugs
01-08-2008 · EurekAlert!
Lifestyle intervention and the drug metformin are both effective against antipsychotic-induced weight gain, and treatment is most effective when the two therapies are combined, according to a study in the Jan. 9/16 issue of JAMA.
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- Weight gain induced by antipsychotic drugs can be avoided
01-16-2008 · EurekAlert!
A research team from Universite Laval's Faculty of Medicine and Robert-Giffard Hospital has demonstrated that weight gain induced by the use of antipsychotic drugs -- which in extreme cases can be as high as 30 kilos in only one month -- can be avoided through a specially designed weight control program. The researchers report the details of their findings in a recent edition of the Australian and New Zealand Journal of Psychiatry.
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- Hepatitis B drug can compromise HIV treatment
06-20-2007 · EurekAlert!
Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal. In findings published in the New England Journal of Medicine, researchers reported that a patient infected with both hepatitis B and HIV who was treated with entecavir developed a mutant strain of HIV that is resistant to the antiviral drugs lamivudine and emtricitabine.
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- 'Exercise pill' switches on gene that tells cells to burn fat
04-29-2007 · EurekAlert!
By giving ordinary adult mice a drug -- a synthetic designed to mimic fat -- scientists are now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise. The resulting shift in energy balance (calories in, calories burned) makes the mice resistant to weight gain on a high fat diet.
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- Studies look at how genes affect antipsychotic drug response
11-09-2006 · EurekAlert!
Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause.
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- Researchers discover possible markers for mental illness
12-03-2007 · EurekAlert!
Researchers have discovered natural genetic differences that might help predict the most effective antipsychotic drugs for particular patients with mental disorders such as schizophrenia, Parkinson's and drug addiction. They found the differences in the gene for a molecule called the dopamine D2 receptor, a protein present on brain cells that are sensitive to the neurotransmitter dopamine.
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- Plants can be used to study how and why people respond differently to drugs
09-26-2007 · EurekAlert!
While prescription medications work successfully to cure an ailment in some people, in others the same dose of the same drug can cause an adverse reaction or no response at all. According to a research team led by UC Riverside's Sean Cutler, such variation in drug responses can be analyzed by studying much simpler organisms -- like plants.
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- Enzyme structure reveals new drug targets for cancer and other diseases
02-14-2008 · EurekAlert!
Researchers now have a clearer understanding of how a key protein controls gene activity and how mutations in the protein may cause disease. The work could provide new avenues to design drugs aimed at cancer, diabetes, HIV, and heart disease.
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- Not-So-Artful Dodgers: Countering drug tests with niacin proves dangerous
04-07-2007 · Science News Online
Attempts to cleanse illicit drugs from one's body by taking large doses of niacin can cause life-threatening reactions.
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