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Cancer treatment targets tumor blood supply in patients
03-02-2007 · EurekAlert!An antibody called J591 specifically targets an antigen found in high amounts on both prostate tumors and on blood vessels of all solid tumors, according to a study by researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.
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Keywords: cancer, treatment, targets, tumor, blood, supply, patients, target, patient
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- Blood test may help signal tumor's remission, return in throat cancer patients
06-01-2007 · EurekAlert!
A blood test that detects proteins commonly released by a growing tumor could one day become a useful tool for monitoring the effectiveness of chemotherapy and radiation treatment in people with advanced throat cancer, according to a study published in the June 1, 2007, issue of Clinical Cancer Research.
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- Promising treatment target found in Hodgkin lymphoma
07-30-2007 · EurekAlert!
Dana-Farber Cancer Institute scientists have identified a protein that prevents the body's immune system from recognizing and attacking Hodgkin lymphoma cells. Based on this finding, the researchers are now investigating targeted therapies to disable this molecular "bodyguard" and boost a patient's ability to fight the blood cancer.
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- Potential New Target For Skin Cancer Treatment
10-05-2006 · ScienceDaily
When normal skin cells become a melanoma tumor, they sometimes turn on genes not usually found in the skin. According to researchers at the University of Virginia Health System, some of these genes are normally active in the male testis at the time sperm are formed. The genes, called cancer-testis antigens, could be useful targets for drugs that could selectively kill a melanoma tumor, while sparing the rest of the body's tissues.
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- Mayo Clinic Cancer Center -- individualizing treatment for multiple myeloma patients
12-10-2006 · EurekAlert!
Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient's chance of responding to the agent.
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- How can we know early who will benefit from tumor target therapy?
11-21-2007 · EurekAlert!
A 55-year-old male patient had developed advanced hepatic metastasis and peritoneal carcinomatosis after remnant gastric cancer resection three months earlier. The patient only received target therapy, including Cetuximab plus recombinant human endostatin treatment. Anti-tumor activity assessed by 18F-fluorodeoxyglucose positron emission tomography/computer tomography scan at baseline, then every four weeks afterward showed that 18FDG-PET/CT could make an early prediction of the response to cetuximab plus Endostar in such clinical situations.
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- Study shows blood markers can help choose best dose for antiangiogenic drugs
10-25-2007 · EurekAlert!
Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is critical to tumor growth. While these antiangiogenic drugs are effective, at present there are no reliable methods for determining whether they are working, if the right dose is used, or if a patient will benefit from treatment.
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- Genes set scene for metastasis
04-11-2007 · EurekAlert!
Biologists at Memorial Sloan-Kettering Cancer Center have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights targets for therapeutic treatment.
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- Drug combination might offer hope for patients deadly brain tumors
10-18-2007 · EurekAlert!
Brain cancer patients with the poorest prognosis -- those with a type of deadly tumor known as glioblastoma multiforme -- may survive longer with a drug that chokes off a tumor's blood supply.
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- Pre-treatment blood test could guide lung cancer therapy
06-05-2007 · EurekAlert!
A multi-center team, led by Vanderbilt-Ingram Cancer Center investigators, has developed a new pre-treatment blood test that predicts which non-small-cell lung cancer patients will live longer when they are treated with certain targeted cancer therapies (Iressa, Tarceva). The mass spectrometry-based test, described in the June 6 Journal of the National Cancer Institute, may allow physicians to select the most beneficial therapy for each lung cancer patient, a step forward in the era of personalized medicine.
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- New Jefferson trial to test radiation-emitting beads against advanced liver cancer
02-12-2008 · EurekAlert!
Liver cancer specialists at Jefferson's Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer. The therapy entails injecting tiny beads that emit small amounts of radiation into the liver's main artery while also blocking the blood supply feeding the cancer’s growth.
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