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Investigating the measles virus as a tool to kill multiple myeloma

Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure.

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Keywords: investigating, measles, virus, tool, kill, multiple, myeloma, measle, viru

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Similar news on "Investigating the measles virus as a tool to kill multiple myeloma":

1. Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
   08-13-2007 · EurekAlert!
   Two new studies may lead to the development of more effective therapies for individuals with multiple myeloma, a common and incurable blood cell cancer. The research, published by Cell Press in the August issue of the journal Cancer Cell, provides new insight into the molecular mechanisms that underlie aberrant NF-κB activity in MM tumor cells and underscores the relevance of the signaling pathway as a target for MM therapy.
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2. New therapeutic options for newly diagnosed multiple myeloma patients
   12-10-2007 · EurekAlert!
   Mayo Clinic researchers today presented results of a phase II trial of myeloma induction therapy -- a first step therapy designed to reduce cancer cells numbers -- with cyclophosphamide, bortezomib, and dexamethasone (Cybor-D) showing an improved response over the traditional lenalidomide-dexamethasone (L-Dex) therapy.
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3. Recently discovered virus associated with pediatric respiratory tract infection in Germany
   11-20-2007 · EurekAlert!
   Using a rapid, sensitive, and inexpensive diagnostic tool called MassTag PCR, scientists at Columbia University Mailman School of Public Health's Center for Infection and Immunity implicated a new human rhinovirus as the cause of severe pediatric respiratory tract infections in Europe.
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4. Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer
   10-30-2006 · EurekAlert!
   Mayo Clinic Cancer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor.
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5. How to design a cancer-killing virus
   10-25-2007 · EurekAlert!
   One new way to treat individuals with cancer that is being developed is the use of viruses that infect and kill cancer cells while leaving normal cells unharmed. These viruses are known as virotherapeutics. In a new study in the Journal of Clinical Investigation the development of a new virotherapuetic that had antitumor effects in both mice and rabbits is described.
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6. 10 million people a year are affected by zoonotic viruses spread by non-human hosts
   11-08-2006 · EurekAlert!
   An estimated 50 million people were affected by zoonotics diseases, including H5N1 (bird flu), SARS and Rabies, between 2000 and 2005 and up to 78,000 died. No effective vaccines exist for the most common diseases. And the Dengue virus, which caused about a third of the deaths is experiencing a global resurgence. Zoonotic diseases can become serious killers if they adapt to human to human transmission -- HIV and Measles are two examples.
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7. UCI scientists reconstruct migration of avian flu virus
   03-05-2007 · EurekAlert!
   UC Irvine researchers have combined genetic and geographic data of the H5N1 avian flu virus to reconstruct its history over the past decade. They found that multiple strains of the virus originated in the Chinese province of Guangdong, and they identified many of the migration routes through which the strains spread regionally and internationally.
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8. Emory researchers identify signaling protein for multiple myeloma
   09-10-2007 · EurekAlert!
   Researchers at Emory University's Winship Cancer Institute are the first to discover a mechanism that plays a critical role in the multiple myeloma cell cycle and survival. Their research may result in identification of a new therapeutic target for treating multiple myeloma.
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9. Studies attribute recent increase in multiple myeloma survival to novel therapies
   11-01-2007 · EurekAlert!
   Multiple myeloma is one of the most common and devastating bone marrow cancers in the US, but survival rates have risen dramatically over the past decade. Recent analyses suggest that this trend may be attributed to new types of drugs and aggressive therapeutic interventions such as stem cell transplantation, according to the results of two studies prepublished online in Blood, the official journal of the American Society of Hematology.
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10. 3-drug combination 'extremely promising' as first-line therapy for multiple myeloma
    12-11-2007 · EurekAlert!
    A new combination of bortezomib (Velcade) and two other drugs is showing a very high response rate in patients newly diagnosed with multiple myeloma, a team headed by Dana-Farber Cancer Institute investigators reported at the annual meeting of the American Society of Hematology.
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