Daily non-political popular news in brief.
Gene tests and brain imaging reveal early dementia
03-06-2007 · EurekAlert!Dementia diseases develop insidiously and are generally discovered when the memory has already started to deteriorate. New research form Swedish medical university Karolinska Institutet shows, however, that approaching Alzheimer's can be detected several years before the symptoms manifest themselves.
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Keywords: gene, tests, brain, imaging, reveal, dementia, test
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- Obesity research boosted by watching hunger in the brain
11-07-2007 · EurekAlert!
Scientists can now measure how full or hungry a mouse feels, thanks to a new technique which uses imaging to reveal how neurons behave in the part of the brain which regulates appetite. Researchers hope the technique, which uses magnetic resonance imaging, will enable a far greater understanding of why certain people become obese when others do not, and why different people have different appetites.
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- Genesearch Breast Lymph Node assay detects breast cancer metastases with greater sensitivity
12-16-2006 · EurekAlert!
Results from a prospective clinical study show that the GeneSearch™ Breast Lymph Node (BLN) Assay, a gene-based diagnostic test has greater sensitivity than traditional intra-operative methods of detecting the spread of breast cancer to the lymph nodes. In the study sponsored by Veridex, LLC, the GeneSearch™ BLN Assay demonstrated overall sensitivity at least 10 percentage points higher than traditional intra-operative tests. The data were presented today at the 29th annual San Antonio Breast Cancer Symposium.
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- New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
06-27-2007 · EurekAlert!
A new genetic test targeting the most common types of muscular dystrophy -- those caused by mutations in the dystrophin gene -- is far quicker with greater accuracy and sensitivity than existing tests. It can be used to confirm clinical diagnoses, to test female family members who may be carriers, and to perform prenatal testing.
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- Fast test for low blood flow in dogs detects early heart trouble
11-12-2006 · EurekAlert!
Working with dogs and using the latest in imaging software and machinery, also known as a 64-slice CT scanner, Johns Hopkins heart specialists have developed a fast and accurate means of tracking blood that has been slowed down by narrowing of the coronary arteries. Researchers say it took them less than half the time of exercise stress tests and echocardiograms currently used to find early warning of vessels more likely to become blocked and cause heart attack.
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- High-normal uric acid linked with mild cognitive impairment in the elderly
01-01-2007 · EurekAlert!
Researchers at the Johns Hopkins and Yale university medical schools have found that a simple blood test to measure uric acid, a measure of kidney function, might reveal a risk factor for cognitive problems in old age. Of 96 community-dwelling adults aged 60 to 92 years, those with uric-acid levels at the high end of the normal range had the lowest scores on tests of mental processing speed, verbal memory and working memory.
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- Possible genetic link to schizophrenia identified
02-08-2007 · EurekAlert!
Several neurological and psychiatric disorders, including schizophrenia, are associated with changes in the brain that affect nerves that communicate with each other using dopamine. One protein that is crucial for dopamine-mediated neuronal communication in animals is DARPP-32. Now, researchers have shown that the gene that encodes DARPP-32 in humans exhibits genetic variation and that one particular variant is associated with increased performance in a number of cognitive tests and with an increased risk of schizophrenia.
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- Cognitive scores vary as much within test takers as between age groups making testing less valid
07-01-2007 · EurekAlert!
How precise are tests used to diagnose learning disability, progressive brain disease or impairment from head injury? Timothy Salthouse, Ph.D., a noted cognitive psychologist at the University of Virginia, has demonstrated that giving a test only once isn't enough to get a clear picture of someone's mental functioning. It appears that repeating tests over a short period may give a more accurate range of scores, improving diagnostic workups.
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- Cortex area thinner in youth with Alzheimer's-related gene
04-23-2007 · EurekAlert!
A part of the brain first affected by Alzheimer's disease is thinner in youth with a risk gene for the disorder, a brain imaging study has found. A thinner entorhinal cortex may render these youth more susceptible to degenerative changes and mental decline later in life. This learning and memory hub is thinner in youth with the Alzheimer's-releated ApoE4 variant of the apolipoprotein gene, perhaps lowering the threshold for adverse consequences with aging-related tissue loss.
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- Annals of Internal Medicine tip sheet for Oct. 2
10-01-2007 · EurekAlert!
The following press releases are attached to the upcoming issue of Annals of Internal Medicine: "Organizations Issue Comprehensive Guidelines for Treating Low Back Pain: Clinicians Shouldn't Routinely Order Imaging and Other Diagnostic Tests"; "Trial of Two Drugs Finds One Better at Suppressing Hepatitis B Virus"; and "All Screening Models for Breast Cancer-Causing Gene Mutations Work, with Reservations."
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- Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
09-27-2007 · EurekAlert!
Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.
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