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Researchers discover gene essencial to cerebellum formation
03-06-2007 · EurekAlert!A study published this week in the scientific journal PNAS provides new information on the origin of different cells in the cerebellum, an important component of the central nervous system found in all vertebrates, including humans, and the part of the brain that controls movement.
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Keywords: researchers, discover, gene, essencial, cerebellum, formation, researcher
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- Researchers discover inherited mutation for leukemia
05-31-2007 · EurekAlert!
Researchers have discovered the first inherited gene mutation that increases a person's risk for chronic lymphocytic leukemia, one of the most common forms of the disease. The study shows that the inherited mutation greatly reduces the gene's protective activity. Furthermore, a second kind of change occurs later that turns the gene off altogether, leading to leukemia. This latter alteration is a chemical change that is not inherited.
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- Penn researchers discover how microRNAs control protein synthesis
07-09-2007 · EurekAlert!
While most RNAs work to create, package and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a regulatory protein to halt protein production.
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- UGA scientists discover bacterial 'switch gene' that regulates oceans' sulfur emissions into the air
10-26-2006 · EurekAlert!
A team of researchers, led by marine microbial ecologist Mary Ann Moran at the University of Georgia, has discovered a bacterial "switch gene" in two groups of plankton. This gene helps determine whether certain marine bacterioplankton convert a sulfur compound to one that rises into the atmosphere and affects the earth's temperature or remains climatically inactive in the seas.
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- Cold Spring Harbor Laboratory scientists discover new gene that prevents multiple types of cancer
02-09-2007 · EurekAlert!
A decades-old cancer mystery has been solved by researchers at Cold Spring Harbor Laboratory (CSHL). "We not only found a critical tumor suppressor gene, but have revealed a master switch for a tumor suppressive network that means more targeted and effective cancer therapy in the future," said CSHL Associate Professor Alea Mills, Ph.D. The study, headed by Mills, was published in the February issue of Cell.
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- Penn researchers discover initial steps in the development of taste
12-05-2006 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine are closer to understanding how the sense of taste develops. They have pinpointed a molecular pathway that regulates the development of taste buds. Using genetically engineered mice, they discovered that a signaling pathway activated by small proteins called Wnts is required for initiating taste-bud formation. They have also determined that Wnt proteins are required for hooking up the wiring of taste signals to the brain.
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- UD researchers discover promising technique for repairing gene that causes spinal muscular atrophy
02-11-2008 · EurekAlert!
Researchers at the University of Delaware have discovered a novel technique -- that acts like a "spell-checker" for correcting a misspelling in the DNA code -- to repair the defective gene that causes spinal muscular atrophy. This hereditary neuromuscular disease is the number-one genetic killer of children under two years old.
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- MGH Cancer Center researchers find new gene associated with Wilms tumor
01-04-2007 · EurekAlert!
Researchers at the Massachusetts General Hospital Cancer Center have discovered a novel gene mutation associated with Wilms tumor, the most common pediatric kidney cancer. The newly identified gene is mutated in about 30 percent of cases of Wilms tumor and is located on the sex-determining X chromosome, which means that a single altered copy would be sufficient for tumor formation.
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- Gene found to play a suppressor role in skin cancer development
02-06-2008 · EurekAlert!
Researchers at the Burnham Institute for Medical Research have provided genetic evidence that Activating Transcription Factor 2 plays a suppressor role in skin cancer development. ATF2 is a protein that regulates gene transcription, the first step in the translation of genetic code, in response to extracellular stresses such as ultraviolet light and ionizing radiation. This function of ATF2 in stress and DNA damage response suggests it may also play a role in tumor formation.
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- Scientists discover a new risk factor for Alzheimer's
01-14-2007 · EurekAlert!
Researchers led by Howard Hughes Medical Institute international research scholar Peter St George-Hyslop have identified a new genetic risk factor associated with the most common form of Alzheimer's disease. The research implicates a gene called SORL1 in late-onset Alzheimer's, which usually strikes after age 65.
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- UD researchers discover technique for repairing gene defect that causes spinal muscular atrophy
02-11-2008 · EurekAlert!
Researchers at the University of Delaware have discovered a novel technique -- that acts like a "spell-checker" for correcting a misspelling in the DNA code -- to repair the defective gene that causes spinal muscular atrophy. This hereditary neuromuscular disease is the number-one genetic killer of children under two years old.
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