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Researchers identify ovarian cancer biomarkers

03-07-2007 · EurekAlert!

Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while preliminary, could one day improve screening, diagnosis and treatment for this disease.

Keywords: researchers, identify, ovarian, cancer, biomarkers, researcher, biomarker

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Newly identified biomarker detects and regulates spread of brain tumors
11-10-2006 · EurekAlert!
Researchers have identified a novel biomarker for brain tumors and have uncovered a potential role the marker may play when the tumor spreads or comes back after treatment. The biomarker, a protein known as "soluble attractin," is normally absent in the central nervous system and is undetectable in cerebral spinal fluid unless malignant astrocytomas are present in the CNS. This newfound ability to identify biomarkers for malignant astrocytomas means physicians will have a minimally invasive method to track the success of treatments.
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Researchers find two biomarkers with potential to predict breast cancer spread
12-15-2006 · EurekAlert!
Expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes, according to researchers who say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize.
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New biomarker test could predict outcome for bladder cancer patients
02-01-2007 · EurekAlert!
A set of molecular biomarkers might better predict the recurrence of bladder cancer than conventional prognostic features such as the stage or grade of the malignancy at the time it is discovered, UT Southwestern Medical Center researchers have found.
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New biomarker test could predict outcome for bladder cancer patients
02-01-2007 · UT Southwestern Medical Center
A set of molecular biomarkers might better predict the recurrence of bladder cancer than conventional prognostic features such as the stage or grade of the malignancy at the time it is discovered, UT Southwestern Medical Center researchers have found.
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OHSU Cancer Institute, VA researchers find way to identify which men need a second biopsy
06-02-2007 · EurekAlert!
A researcher in the Oregon Health & Science University Cancer Institute and Portland Veterans Affairs Medical Center has found a way to identify which men need a second prostate biopsy because they may be harboring life-threatening prostate cancer even though they were given a clean bill of health after their first biopsy.
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Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer
04-15-2007 · EurekAlert!
Researchers at Columbia University's Mailman School of Public Health have discovered a means for early detection of liver cancer. Using DNA isolated from serum samples as a baseline biomarker, the scientists examined changes in certain tumor suppressor genes that have been associated with the development of liver carcinomas. This is the first study to prospectively examine potential biomarkers for early detection of liver cancer in high-risk populations.
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Gold nanoparticle probes may allow earlier cancer detection
12-23-2007 · EurekAlert!
Using tiny gold particles embedded with dyes, researchers have shown that they can identify tumors under the skin of a living animal. These tools may allow doctors to detect and diagnose cancer earlier and less invasively. Studded with antibody fragments called ScFv peptides that bind cancer cells, the gold particles grab onto tumors after their injection into a mouse. When illuminated with a laser beam, the tumor-bound particles send back a signal that is specific to the dye.
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No magic tomato? Study breaks link between lycopene and prostate cancer prevention
05-17-2007 · EurekAlert!
Tomatoes might be nutritious and tasty, but don't count on them to prevent prostate cancer. In the May issue of Cancer Epidemiology, Biomarkers & Prevention, researchers based at the National Cancer Institute and Fred Hutchinson Cancer Research Center report that lycopene, an antioxidant predominately found in tomatoes, does not effectively prevent prostate cancer. In fact, the researchers noted an association between beta-carotene, an antioxidant related to lycopene, and an increased risk for aggressive prostate cancer.
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Estrogen interferes with immune surveillance in breast cancer
01-24-2007 · EurekAlert!
Estrogen is known to enhance the growth and migration of breast cancer cells. Now researchers at the University of Illinois at Urbana-Champaign have found that estrogen also can shield breast cancer cells from immune cells.This is the first study to identify estrogen’s role in shielding breast cancer cells from the action of immune cells.
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Researchers identify cell pathway in colon cancer
02-20-2007 · EurekAlert!
Researchers have identified a cell pathway which plays a critical role in the development of colon cancer. This pathway may also play a role in the development of lung and stomach cancers. Investigators say they have identified STAT3 {signal transducer and activator of transcription 3}, as a target regulated by PTPRT {Receptor Protein tyrosine phosphatase T}, which was previously identified to be mutated in colon, lung and stomach cancer patients.
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