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Super Chow, Laced With Semi-synthetic Vitamin E Derivative, Inhibited Spread Of Cancer In Mice
10-02-2006 · ScienceDailyA chemically altered form of vitamin E mixed into mouse chow dramatically reduced spread of aggressive mammary cancer in mice, suggesting that the compound in pill form could be used to treat human metastatic cancer, according to a report in the October 1 issue of the journal Cancer Research.
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Keywords: super, chow, laced, semi-synthetic, vitamin, derivative, inhibited, spread, cancer, mice, semi, synthetic
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- Synthetic peptide targets latent papilloma virus infections
01-02-2007 · EurekAlert!
Infection with the human papilloma virus, the major cause of cervical cancer, is forever. The virus remains latent in skin cells, ready to flare up at any time to create warts on the skin or the genitals. A new finding by UC Berkeley's Michael Botchan and colleagues offers hope that a drug can halt spread of the virus into new cells, and perhaps even eliminate the virus from the body.
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- Mouse mammary tumor virus can replicate in human cells
10-10-2007 · EurekAlert!
Mouse mammary tumor virus -- which causes mammary cancer in mice -- can replicate and spread in human cells, research published this week shows. The study, published in the online open access journal Retrovirology, adds weight to the theory that MMTV might be involved in causing human breast cancer.
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- Synthetic compound promotes death of lung-cancer cells, tumors
11-12-2007 · UT Southwestern Medical Center
Human lung-cancer tumors grown in mice have been shown to regress or disappear when treated with a synthetic compound that mimics the action of a naturally occurring “death-promoting” protein found in cells, researchers at UT Southwestern Medical Center report.
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- Agents of Metastasis: Four proteins conspire in breast cancer spread
04-14-2007 · Science News Online
Four proteins work together to assist cancer growth and metastasis, and drugs against them inhibit both processes, tests in mice suggest.
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- Small RNAs can prevent spread of breast cancer
01-09-2008 · EurekAlert!
Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid that suppress the spread of breast cancer to the lungs and bone. The new research shows that the most invasive and aggressive human breast cancer tumors are missing three critical microRNA molecules. When the researchers put those molecules back into human breast cancer tumors in mice, the tumors lost their ability to spread.
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- A genetic 'gang of 4' drives spread of breast cancer
04-11-2007 · EurekAlert!
Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs. The new studies by Howard Hughes Medical Institute researchers reveal that the aberrant genes work together to promote the growth of primary breast tumors. Cooperation among the four genes also enables cancerous cells to escape into the bloodstream and penetrate through blood vessels into lung tissues.
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- Vitamin A derivative associated with reduced growth in some lung cells
10-30-2007 · EurekAlert!
Treatment with a derivative of vitamin A called retinoic acid was associated with reduced lung cell growth in a group of former heavy smokers, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.
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- Genes set scene for metastasis
04-11-2007 · EurekAlert!
Biologists at Memorial Sloan-Kettering Cancer Center have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights targets for therapeutic treatment.
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- 2 microRNAs promote spread of tumor cells
01-28-2008 · EurekAlert!
Scientists at The Wistar Institute and their colleagues have identified two microRNAs that promote tumors' deadly spread. One of the miRNAs may provide an early warning of metastatic breast cancer and the need for aggressive treatment. In a study to be published Feb. 1 in Nature Cell Biology that is available online, the researchers describe how two miRNAs transformed non-invasive human breast cancer cells into cells that rapidly metastasized in cell cultures and mice.
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- Grape seed extract halts cell cycle, checking growth of colorectal tumors in mice
10-18-2006 · EurekAlert!
Chemicals found in grape seeds significantly inhibited growth of colorectal tumors in both cell cultures and in mice, according to researchers who have already demonstrated the extract's anti-cancer effects in other tumor types.
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