Daily non-political popular news in brief.
Gene therapy for blindness clears hurdle in mice
03-14-2007 · EurekAlert!University of Florida Genetics Institute researchers were able to use interfering RNA in experiments with mice to quiet a gene that plays a crucial role in a leading cause of inherited blindness. Disabling the gene is a step toward developing a gene therapy to treat people with retinitis pigmentosa, an inherited disease that attacks the light-sensing cells in the eye.
Read more »
Keywords: gene, therapy, blindness, clears, hurdle, mice, clear
« Previous | Next »
Similar news on "Gene therapy for blindness clears hurdle in mice":
- Light-sensitive photoswitches could restore sight to those with macular degeneration
10-31-2006 · EurekAlert!
The major cause of blindness in this country is the death of photoreceptors -- rods and cones -- in the retina, a disease called macular degeneration. A possible new therapy involves inserting photoswitches into surviving retinal cells, giving them the gift of sight. NIH's nanomedicine initiative just awarded UC Berkeley and Lawrence Berkekley National Laboratory scientists $6 million to pursue this technique in mice.
Similar news · Read more »
- Genetic hearing loss may be reversible without gene therapy
02-22-2007 · EurekAlert!
A large proportion of genetically caused deafness in humans may be reversible by compensating for a missing protein. Researchers have found that in mice, increasing the amount of the protein connexin26 in the ear's cochlea compensates for an absence of another protein, connexin30. The findings come 10 years after scientists first discovered that connexin26 mutations cause much of the deafness diagnosed at birth.
Similar news · Read more »
- Dual gene therapy suppresses lung cancer in preclinical test
01-15-2007 · EurekAlert!
Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center report in the January 15 edition of Cancer Research.
Similar news · Read more »
- Reprogrammed human adult stem cells rescue diseased muscle in mice
12-12-2007 · EurekAlert!
Scientists report that adult stem cells isolated from humans with muscular dystrophy can be genetically corrected and used to induce functional improvement when transplanted into a mouse model of the disease. The research, published by Cell Press in the December issue of Cell Stem Cell, represents a significant advance toward the future development of a gene therapy that uses a patient's own cells to treat this devastating muscle-wasting disease.
Similar news · Read more »
- Intravenous gene therapy protects normal tissue of mice during whole-body radiation
11-07-2006 · EurekAlert!
Gene therapy administered intravenously could be used as an agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb. In the University of Pittsburgh study, mice were used to test the protective effects of manganese superoxide dismutase plasmid liposome (MnSOD-PL) gene therapy on the bone marrow during whole-body irradiation.
Similar news · Read more »
- Penn researchers report that gene therapy awakens the brain despite blindness from birth
06-25-2007 · EurekAlert!
Researchers at the University of Pennsylvania have demonstrated that gene therapy used to restore retinal activity to the blind also restores function to the brain's visual center, a critical component of seeing.
Similar news · Read more »
- Disease outbreak detection, retinal gene therapy
06-25-2007 · EurekAlert!
In this issue: An epidemiological network model for disease outbreak detection, and Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation.
Similar news · Read more »
- Gene therapy safety trial for childhood blindness under way
11-19-2007 · EurekAlert!
A gene-transfer technique is being tested for safety in people in a phase 1 clinical research study of inherited blindness conducted by the University of Pennsylvania and the University of Florida with support from the National Eye Institute of the National Institutes of Health. The first adult subject underwent the procedure last week.
Similar news · Read more »
- Ultrathin films deliver DNA as possible gene therapy tool
03-26-2007 · EurekAlert!
Gene therapy -- the idea of using genetic instructions rather than drugs to treat disease -- has tickled scientists' imaginations for decades, but is not yet a viable therapeutic method. One sizeable hurdle is getting the right genes into the right place at the right time. Engineers at the University of Wisconsin-Madison are now developing a tool to tackle this problem.
Similar news · Read more »
- JCI table of contents: Nov. 1, 2006
11-01-2006 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Nov. 1, 2006, in the JCI, including: Lack of GBA2: a contraceptive for male mice; Decreased TGF-beta signaling might make you demented; Gene therapy a possibility for metachromatic leukodystrophy?; Prostaglandins help plug a hole after birth; Why PSCK9 raises cholesterol levels; NF-kappa-B contributes to muscle wasting, and Lung DCs legitimate targets for treating asthma.
Similar news · Read more »
