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Affymetrix 500K array used to identify memory gene
10-19-2006 · EurekAlert!Affymetrix Inc., announced today that researchers at the Translational Genomics Research Institute in Phoenix, Ariz., have used the Affymetrix 500K Array to discover a gene -- called Kibra -- associated with memory performance in humans. The team's findings may be used to develop new medicines for memory-based diseases such as Alzheimer's and Parkinson's by providing scientists with a better understanding of how memory works at the molecular level.
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Keywords: affymetrix, 500k, array, used, identify, memory, gene
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12-05-2007 · EurekAlert!
Gene-expression profiles might be used to identify prognostic biomarkers for Kawasaki disease, and help to unravel the underlying biology of the illness, research published this week in the online open access journal Genome Biology reveals. The new findings also support the idea that gene-expression profiles might be used to generate biomarkers for other systemic inflammatory illnesses.
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- A molecular map for aging in mice
11-28-2007 · EurekAlert!
Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues. The study, published Nov. 30 in PLoS Genetics, uses a newly available database called AGEMAP to document the process of aging in mice at the molecular level. The work describes how aging affects different tissues in mice, and ultimately could help explain why lifespan is limited to just two years in mice.
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- UCLA scientists identify new genetic link to autism
01-10-2008 · EurekAlert!
UCLA scientists used language onset -- the age when a child speaks his first word -- as a tool for identifying a new gene linked to autism. The team also discovered that the gene is most active in developing brain regions involved with language and thought. Interestingly, evidence for the genetic link came from the DNA of families with autistic boys, not those with autistic girls.
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- 'Network' approach identifies potential breast cancer susceptibility gene
10-09-2007 · EurekAlert!
Like a crossword-puzzle solver who uses the letters in some answers to figure out others, researchers at Dana-Farber Cancer Institute and an international group of collaborators have used data on genes involved in inherited forms of breast cancer to identify a gene linked to non-hereditary cases of the disease.
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- Pioneering study looks at p53’s Role in tumor-stroma interactions
10-25-2006 · EurekAlert!
Researchers have conducted the first comprehensive study of the role an important tumor suppressor gene plays in cancer development. P53 is known as a major tumor suppressor that is frequently mutated in human cancer. In this study, researchers used novel proteomic techniques to identify the proteins secreted by cells specifically in response to p53. The findings suggest a newfound role for wt-p53 in the control of the tumor's ability to communicate with the normal stromal cells surrounding it.
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- Taking 'chips' to the next level of gene hunting
11-14-2006 · EurekAlert!
Researchers at the Johns Hopkins' High Throughput Biology Center have invented two new gene "chip" technologies that can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be "junk."
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10-25-2006 · EurekAlert!
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- Researchers first to map gene that regulates adult stem cell growth
01-14-2007 · EurekAlert!
A new discovery in stem cell research may mean big things for cancer patients in the future. After being the first to genetically map and identify a gene that regulates adult stem cells, the researchers investigated the gene's protein product, Latexin, which can be used to ramp up the body's stem cell count. The team's findings are being published in Nature Genetics.
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03-21-2007 · EurekAlert!
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- Research team identifies human 'memory gene'
10-19-2006 · EurekAlert!
Researchers at the Translational Genomics Research Institute (TGen) today announced the discovery of a gene that plays a significant role in memory performance in humans. The study details how researchers associated memory performance with a gene called Kibra in over 1,000 individuals -- both young and old -- from Switzerland and Arizona. This study is the first to describe scanning the human genetic blueprint at over 500,000 positions to identify cognitive differences between humans.
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