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Study describes action of estrogen in protecting bone
03-23-2007 · EurekAlert!Researchers at the University at Buffalo have described a novel pathway by which estradiol, the primary estrogen in humans, aids in maintaining bone density, a function critical to avoiding osteoporosis.
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Keywords: study, describes, action, estrogen, protecting, bone, describe
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- Study shows drug effective in treating, preventing breast cancer
11-01-2007 · EurekAlert!
A new study of an estrogen-derived drug shows promise as a treatment for breast cancer and breast cancer metastases to bone.
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- Estrogen interferes with immune surveillance in breast cancer
01-24-2007 · EurekAlert!
Estrogen is known to enhance the growth and migration of breast cancer cells. Now researchers at the University of Illinois at Urbana-Champaign have found that estrogen also can shield breast cancer cells from immune cells.This is the first study to identify estrogen’s role in shielding breast cancer cells from the action of immune cells.
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- Other highlights in the November 1 JNCI
10-31-2006 · EurekAlert!
Other highlights in the November 1 issue of JNCI include a review of statins and fibrates for action against melanoma, a study of a virus that kills brain tumors in mice, an antibody that decreases ovarian cancer growth in mice and a study that describes the use of the immunohistochemical assay in predicting clinical trial results for breast cancer patients.
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- Leukemia drug turns mini-molecules up, cancer genes down
03-01-2007 · EurekAlert!
New research shows that a form of vitamin A used to treat acute promyelocytic leukemia induces changes in an unusual class of small molecules called microRNAs (miRNAs) in the leukemic cells. The study also shows that three of these miRNAs inhibit the action of two genes important for cancer development, helping to explain how the drug works.
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- Math model could aid study of collagen ailments
11-14-2006 · EurekAlert!
An MIT researcher's mathematical model explains for the first time the distinctive structure of collagen, a material key to healthy human bone, muscles and other tissues. The new model shows collagen's structure from the atomic to the tissue scale. An improved understanding of nature's most abundant protein could aid the search for cures to such ailments as osteoporosis and scurvy, all recognized as arising from diseased collagen.
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- Preventing graft-vs.-host disease after bone marrow transplant -- without toxicity
12-11-2006 · EurekAlert!
Most patients undergoing bone-marrow transplant must receive powerful chemotherapy drugs to suppress their immune system and prevent their bodies from rejecting the donated cells. New research shows that this chemotherapy increases the risk for graft-versus-host disease -- but also suggests that this risk can be reduced by replacing a natural antibiotic that's depleted when patients undergo chemotherapy. A multicenter study led by Children's Hospital Boston and the Dana-Farber Cancer Institute is about to test this idea.
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- Scientists identify a candidate gene for osteoporosis
03-28-2007 · EurekAlert!
Researchers report the identification of a gene that may play a role in susceptibility to osteoporosis -- the crippling disease that leads to bone fractures, especially of the hip and spine. The study, conducted by scientists at the Musculoskeletal Diseases Center of the Jerry L. Pettis Memorial Veteran's Affairs Medical Center at Loma Linda, shows convincing evidence that a gene called DARC negatively regulates bone density in mice.
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- Walking prevents bone loss caused from prostate cancer treatment
10-28-2007 · EurekAlert!
Exercise may reduce, and even reverse, bone loss caused by hormone and radiation therapies used in the treatment of localized prostate cancer, thereby decreasing the potential risk of bone fractures and improving quality of life for these men, according to a study presented on Oct. 28, 2007, at the American Society for Therapeutic Radiology and Oncology's 49th Annual Meeting in Los Angeles.
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- High-trauma fractures in older adults linked to osteoporosis, increased risk of another fracture
11-27-2007 · EurekAlert!
Contrary to a widely held assumption, high-trauma nonspine fractures in older women and men, such as from a car crash, are associated with low bone mineral density and an increased risk of a subsequent fracture, according to a study in the Nov. 28 issue of JAMA. These findings suggest that older adults who experience these fractures should be evaluated for osteoporosis.
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- New treatment boosts bone healing and regrowth
01-09-2008 · EurekAlert!
A drug originally used to treat iron poisoning can significantly boost the body's ability to heal and regrow injured bones, according to a new study. Bone density following the new treatment more than doubled. Researchers found new blood vessel growth, necessary for bone healing, was achieved through a cell pathway.
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