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Novel DNA changes linked to autism

Genetic alterations that occur in children without being inherited from the parents contribute to certain cases of autism and related developmental disorders.

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Keywords: novel, dna, changes, linked, autism, change

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1. Age-related changes in DNA repair illuminate the connection between age and genetic damage
   10-23-2006 · EurekAlert!
   Researchers have uncovered a new way in which the aging process is linked to DNA damage -- which occurs normally as a result of cell metabolism and environmental influences -- and the various ways in which cells repair that damage. In the new work, researchers found that cells in young fruit flies make use of a different mix of molecular DNA-repair mechanisms compared to cells in older flies.
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2. Researchers Link Ice Age Climate-change Records To Ocean Salinity
   10-07-2006 · ScienceDaily
   Sudden decreases in temperature over Greenland and tropical rainfall patterns during the last Ice Age have been linked for the first time to rapid changes in the salinity of the north Atlantic Ocean, according to research published Oct. 5, 2006, in the journal Nature.
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3. UCLA scientists identify new genetic link to autism
   01-10-2008 · EurekAlert!
   UCLA scientists used language onset -- the age when a child speaks his first word -- as a tool for identifying a new gene linked to autism. The team also discovered that the gene is most active in developing brain regions involved with language and thought. Interestingly, evidence for the genetic link came from the DNA of families with autistic boys, not those with autistic girls.
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4. Evidence From Ice Age That Climate Change Can Have A Rapid Effect On Ocean Circulation
   10-09-2006 · ScienceDaily
   Sudden shifts in temperature over Greenland and tropical rainfall patterns during the last ice age have been linked for the first time to rapid changes in the salinity of the north Atlantic Ocean. The results provide further evidence that climate change can have a direct and rapid impact on ocean circulation and chemistry.
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5. Study finds regions of DNA that appear linked to autistic spectrum disorders
   05-09-2007 · EurekAlert!
   Using an innovative statistical approach, a research team from Washington University School of Medicine in St. Louis and the University of California, Los Angeles, has identified two regions of DNA linked to autism. They found the suspicious DNA with a much smaller sample of people than has been used traditionally in searches for autism genes.
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6. Stretching DNA to the limit
   04-24-2007 · EurekAlert!
   A group of researchers at Duke University have developed a method to measure changes in the mechanical properties of DNA upon irradiation with UV light. This work might pave the way for using stretch-release force spectroscopy measurements in DNA diagnostics.
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7. Linking air pollutants and blood clotting in mice
   09-20-2007 · EurekAlert!
   Air pollution is caused by any particulate matter, chemical or biological agent that changes the natural characteristics of the atmosphere. Exposure to particulate matter has been linked to an increased risk of heart problems, including increased risk of heart attack. A new study in mice has now identified a mechanism by which exposure to particulate matter leads to accelerated blood clotting and thrombosis, something that can precipitate heart attacks and stroke.
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8. Increased hurricane activity linked to sea surface warming
   01-30-2008 · EurekAlert!
   The link between changes in the temperature of the sea’s surface and increases in North Atlantic hurricane activity has been quantified for the first time. The research - carried out by scientists at UCL and due to be published in Nature on Jan. 31 -- shows that a 0.5 C increase in sea surface temperature can be associated with a ~40 per cent increase in hurricane activity.
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9. Researchers demonstrate novel method for studying the DNA binding of small molecules
   06-04-2007 · EurekAlert!
   Northeastern University professor Mark C. Williams and colleague Ioana Vladescu have discovered a novel method for studying the DNA binding of small molecules with unprecedented accuracy. Their paper, titled "Quantifying force-dependent and zero-force DNA intercalation by single-molecule stretching," has been published in the May 2007 issue of the prestigious Nature Methods.
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10. Researchers find gene linked to Crohn's disease
    10-26-2006 · EurekAlert!
    An international team of researchers has identified another gene mutation linked to the inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis. The team, including Johns Hopkins gastroenterologists and geneticists, says the novel mutation is in the interleukin-23 (IL-23) gene receptor present in healthy people without Crohn's disease but rare in those with the disease.
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