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Novel platelet therapy may reduce PCI complications
03-24-2007 · EurekAlert!Despite the availability of numerous antithrombotic therapies, adverse events following percutaneous coronary intervention such as late-stent thrombosis are still a concern for cardiologists, and there's a need for medications that can minimize the risk of these complications but also manage the rate of bleeding. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit evaluates the safety and efficacy of a novel oral thrombin receptor antagonist in reducing PCI complications.
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Keywords: novel, platelet, therapy, pci, complications, complication
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- Fat kills cancer
07-03-2007 · EurekAlert!
Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into "suicide genes" that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association for Cancer Research.
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- Bariatric surgery complication rates high in some hospitals, new HealthGrades ratings and study show
11-13-2006 · EurekAlert!
In-hospital bariatric surgery complication rates vary dramatically among the nation's hospitals, according to a study released today by HealthGrades, the leading healthcare ratings company. The study of 86,520 bariatric-surgery procedures performed over the years 2002 through 2004 finds that a typical patient receiving the procedure in a five-star rated hospital would have, on average, a 66 percent lower chance of developing one or more major inhospital complications compared with a one-star rated hospital.
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- Method to prevent hemorrhagic complications of thrombolytic therapy of blood clots is discovered
07-02-2007 · EurekAlert!
The now reported study led by Dr. Perttu J. Lindsberg from the Helsinki University Central Hospital investigated thrombolytics-related brain hemorrhage formation in an experimental stroke model in rats. It found that, in addition to the clot lysing effect, the drug used for this purpose, alteplase (recombinant tissue plasminogen activator) also possesses proinflammatory properties and activates and degranulates mast cells, a kind of tissue-based immune cell.
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- Breast cancer survival rates improved by novel drug sequence, say researchers
02-12-2007 · EurekAlert!
Changing the way women are treated for breast cancer could improve their overall chance of survival, according to research published today in the Lancet. The new paper shows that switching to a drug called exemestane, two to three years after commencing standard therapy with the drug tamoxifen, can cut the risk of death for certain women by a further 17 percent compared with using tamoxifen alone.
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- For some diabetics, burden of care rivals complications of disease
09-27-2007 · EurekAlert!
Many patients with diabetes say that the inconvenience and discomfort of constant therapeutic vigilance, particularly multiple daily insulin injections, has as much impact on the quality of their lives as an intermediate complication. On average, patients considered the burden of comprehensive diabetes care comparable to that of angina, nerve or kidney damage.
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- Gene therapy, cancer-killing viruses and new drugs highlight novel approaches to cancer treatment
04-17-2007 · EurekAlert!
Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.
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- Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
08-31-2007 · EurekAlert!
A nanoparticle drug delivery system designed for brain tumour therapy has shown promising tumour cell selectivity in a novel cell culture model devised by scientists at The University of Nottingham. The project, conducted jointly by the Schools of Pharmacy, Biomedical Sciences and Human Development, will be featured in the September issue of the Experimental Biology and Medicine.
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- New therapy effectively treats deep vein thrombosis
01-29-2008 · EurekAlert!
A novel treatment for blood clots in the legs appears to be safe and effective, according to a pilot study. The study found that injecting or "lacing" the clot with a fiber-binding thrombolytic agent effectively treats deep vein thrombosis and reduces the risk of subsequent recurrence or bleeding.
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- Three-in-one virus killer prevents common, often fatal infections
10-26-2006 · EurekAlert!
A novel combination therapy drastically reduces the infection rate of three prevalent viruses -- and risk of death -- in transplant patients with compromised immune systems. Trivirus-specific cytotoxic T lymphocytes (CTLs), the first multivirus killer of its kind, called, controlled infections caused by three commonplace viruses -- cytomegalovirus (CMV), Epstein-Barr virus (EBV), and adenovirus -- with no toxicity in a phase 1 trial.
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- Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
09-23-2007 · EurekAlert!
Italian scientists will announce on Monday (Sept. 24) that they have found a new and promising target for anti-tumor therapy in cancer. Professor Saverio Alberti, from the CESI, University of Chieti Foundation, Chieti, will tell the European Cancer Conference that he and his team have found a widespread mechanism for the stimulation of tumor growth in man, and that this is leading to the development of novel diagnostic and therapeutic procedures.
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