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Blocking immune cell action increases Alzheimer's-associated protein deposits
03-27-2007 · EurekAlert!The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder. A report from Massachusetts General Hospital researchers finds that lack of a protein required for recruitment of the brain's primary immune cell led to increased amyloid-beta deposits and earlier death in a mouse model of Alzheimer's disease.
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Keywords: blocking, immune, cell, action, alzheimer, s-associated, protein, deposits, associated, deposit
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