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Light-activated therapy targets DNA components
03-27-2007 · EurekAlert!Chemists and biologists at Virginia Tech continuing to design light-activated molecular systems to attack cancer cells have introduced a DNA targeting component.
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Keywords: light-activated, therapy, targets, dna, components, light, activated, target, component
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- Scientists design a PSA-activated protoxin that kills prostate cancer
11-10-2006 · EurekAlert!
Scientists have found a way of using a protein made by prostate cancer to target and kill the cancer cells themselves. In preliminary studies the new therapy affected only the prostate, without causing damage to other healthy tissues, and now it is being tested in a phase I clinical trial, according to research presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Prague on Friday.
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- Study shows liver an excellent target for cancer gene therapy using viral vectors
02-14-2007 · EurekAlert!
A featured paper in the Feb. 14 issue of Nature Cancer Gene Therapy demonstrates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors, based upon a fundamental new understanding of the differences between cancerous and normal liver cells. The findings signal a new way to treat cancers that have spread to the liver, such as metastatic cancers of the colon and breast.
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- Setting the Stage to Find Drugs Against SARS
11-14-2006 · Brookhaven National Laboratory
Scientists at Brookhaven have set the stage for the rapid identification of compounds to fight against severe acquired respiratory syndrome (SARS), the atypical pneumonia responsible for about 800 deaths worldwide since first recognized in late 2002. Researchers from Brookhaven's biology department and the National Synchrotron Light Source characterized a component of the virus that will be the target of new anti-SARS virus drugs.
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- Setting the Stage to Find Drugs Against SARS
11-17-2006 · Brookhaven National Laboratory
Scientists at Brookhaven have set the stage for the rapid identification of compounds to fight against severe acquired respiratory syndrome (SARS), the atypical pneumonia responsible for about 800 deaths worldwide since first recognized in late 2002. Researchers from Brookhaven's biology department and the National Synchrotron Light Source characterized a component of the virus that will be the target of new anti-SARS virus drugs.
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- Animal study identifies promising new target for brain tumor therapy
05-08-2007 · EurekAlert!
A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers from Duke's Preston Robert Tisch Brain Tumor Center. In animal models, the drug re-engaged the body's cancer-damaged immune system.
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- Comparing Chimp, Human DNA
10-13-2006 · ScienceDaily
Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. Instead, they may contain DNA sequences that control how gene-coding regions are activated and read.
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- Scripps Research study reveals new function of protein kinase pathway in tumor suppression
01-25-2007 · EurekAlert!
Scientists at the Scripps Research Institute have discovered a surprising new function of a well-known signaling pathway that, when activated, can inhibit tumor development. This finding may lead to the development of drugs that can serve as an effective cancer therapy by artificially activating this pathway in cancer cells.
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- New therapeutic insight into duchenne muscular dystrophy
03-31-2007 · EurekAlert!
In the April 1 issue of Genes & Development, Dr. Bruce Spiegelman (Dana Farber Cancer Institute) and colleagues identify a key genetic component of and possible therapeutic target for Duchenne muscular dystrophy.
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- DNA computing targets West Nile Virus, other deadly diseases
10-16-2006 · EurekAlert!
Researchers say that they have developed a DNA-based computer that could lead to faster, more accurate tests for diagnosing West Nile Virus and bird flu. Representing the first 'medium-scale integrated molecular circuit,' it is the most powerful computing device of its type to date, they say. In the future, the new technology could be used to develop instruments that can simultaneously diagnose and treat cancer, diabetes or other diseases, the scientists suggest.
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- Study finds estrogen therapy gives aging brain cells a boost
06-25-2007 · EurekAlert!
Cyclical, long-term estrogen injections protected brain cells from age-related deterioration, according to a new study conducted at Mount Sinai School of Medicine. The study suggests that age is a factor in estrogen treatment and sheds light on the intricate relationship between mind, age, and hormones. The study will be published in the online edition of Proceedings of the National Academy of Sciences during the week of June 25.
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