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EVEREST data on use of tolvaptan published in JAMA and featured at ACC
03-27-2007 · EurekAlert!Once-daily dosing with Otsuka's investigational oral medication tolvaptan, a vasopressin receptor antagonist, was associated with improvements in signs and symptoms of acutely decompensated heart failure in hospitalized patients receiving conventional care, without an adverse effect on their long-term survival versus placebo. These data are from the short- and long-term analyses of the international landmark trial EVEREST published in the March 28 issue of JAMA and presented at ACC.
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- Using additional biopsy-scoring data may help determine prostate cancer prognosis
10-02-2007 · EurekAlert!
Men with certain scores and patterns based on prostate cancer biopsy were found to be at higher risk of PSA-failure, suggesting that this measurement could help predict the risk of prostate cancer recurrence, according to preliminary research published in the Oct. 3 issue of JAMA.
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- A potential biological cause for sudden infant death syndrome
10-31-2006 · EurekAlert!
New autopsy data provide the strongest evidence yet that sudden infant death syndrome (SIDS) is not a "mystery" disease but has a concrete biological basis: abnormalities in the brainstem serotonin system. Based on their findings, published in the November 1 issue of JAMA, researchers at Children's Hospital Boston now hope to develop a diagnostic test to identify newborns at risk, and envision treatments to protect them during the vulnerable period.
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- Many Americans at high risk of vision loss do not have access to eye care
03-12-2007 · EurekAlert!
Data from a national survey suggest that an estimated 60 million American adults are at high risk of vision loss, according to a report published in the March issue of Archives of Ophthalmology, one of the JAMA/Archives journals. Of those adults, one in 12 cannot afford eyeglasses when needed, and about one-half do not get dilated eye examinations on a yearly basis.
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- Statin therapy associated with regression of coronary atherosclerosis with key lipid level changes
02-06-2007 · EurekAlert!
An analysis of data from four clinical trials suggests that statin therapy is associated with regression of coronary atherosclerosis when low-density lipoprotein cholesterol (LDL-C or "bad" cholesterol) is substantially reduced and high-density lipoprotein cholesterol (HDL-C or "good" cholesterol) is increased, but it remains to be determined whether this degree of atherosclerosis regression will translate to meaningful reductions in cardiovascular events, according to a study published in the Feb. 7 issue of JAMA.
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- Racial disparities universal in Medicare health plans, study finds
10-24-2006 · EurekAlert!
Blacks do not achieve the same health outcomes as whites in managed care plans under Medicare, the nation's largest health insurance program, according to a study conducted by Brown Medical School and Harvard Medical School researchers. Published in JAMA, the analysis surprisingly shows that significant racial disparities persist within Medicare plans -- even high-performing ones -- based on outcomes related to control of diabetes, cholesterol and blood pressure.
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- Statins reduce risk of heart attack and stroke in those without heart disease
11-27-2006 · EurekAlert!
Among individuals without cardiovascular disease, taking statins regularly may reduce the risk of major heart and cerebrovascular events such as heart attack and stroke but not coronary heart disease or overall death, according to a meta-analysis of previously published studies, reported in the November 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
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- Study, meta-analysis examine factors associated with death from heatstroke
08-13-2007 · EurekAlert!
Individuals who live in a nursing home or take medication to lower blood pressure appear more likely to die during or following hospitalization for heatstroke, according to a study posted online today that will appear in a later print issue of Archives of Internal Medicine, one of the JAMA/Archives journals. A meta-analysis of previous studies also published online today found that being confined to bed, not leaving home daily or being unable to care for oneself also are associated with death from heatstroke.
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- Fosrenol does not further impact cognitive function deterioration in CKD Stage 5 patients
10-18-2006 · EurekAlert!
Newly published data from a large, two-year trial in the November Kidney International report on the effects of chronic kidney disease on cognitive function in CKD Stage 5 patients with hyperphosphatemia (high serum phosphorus levels in the blood), treated with phosphate binder therapy. This study is particularly relevant, as there is evidence that individuals with reduced renal function experience a significantly greater decline in cognitive function compared to those with normal renal function.
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- Listening in on the birth pangs of Earth's crust
11-23-2006 · EurekAlert!
Geologist Donald Forsyth and students from Brown University on a routine ocean-floor mapping cruise jumped into action when they realized that many of the seafloor seismometers they were supposed to collect had been buried by a recent lava flow. Data from the remaining instruments yielded the first detailed record of seismic vibrations leading up to a seafloor spreading event, published this week in the journal Science.
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- Study finds women less likely than men to have their cholesterol controlled
05-15-2007 · EurekAlert!
Women are significantly less likely than men to have their LDL cholesterol controlled to recommended levels, according to a new study by the National Committee for Quality Assurance (NCQA). The study, to be published in the May/June edition of Women’s Health Issues, investigated gender differences in cardiovascular disease prevention, treatment and risk factors based on national health care quality data from commercial and Medicare managed care plans.
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