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Autism's DNA Trail: Gene variant tied to developmental disorder
10-21-2006 · Science News OnlineA study of more than 700 families with children diagnosed with autism has identified a gene variant, already known to affect brain formation, that boosts a person's chances of developing this severe disorder.
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Keywords: autism, dna, trail, gene, variant, tied, developmental, disorder
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- Cortex area thinner in youth with Alzheimer's-related gene
04-23-2007 · EurekAlert!
A part of the brain first affected by Alzheimer's disease is thinner in youth with a risk gene for the disorder, a brain imaging study has found. A thinner entorhinal cortex may render these youth more susceptible to degenerative changes and mental decline later in life. This learning and memory hub is thinner in youth with the Alzheimer's-releated ApoE4 variant of the apolipoprotein gene, perhaps lowering the threshold for adverse consequences with aging-related tissue loss.
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- Accelerated head growth can predict autism before behavioral symptoms start
01-30-2008 · EurekAlert!
Children with autism have normal-size heads at birth but develop accelerated head growth between six and nine months of age, a period that precedes the onset of many behaviors that enable physicians to diagnose the developmental disorder, according to new research from the University of Washington's Autism Center.
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- Brain regions do not communicate efficiently in adults with autism
10-14-2006 · EurekAlert!
A novel look at the brains of adults with autism has provided new evidence that various brain regions of people with the developmental disorder do not communicate with each other as efficiently as they do in other people.
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- Fragile X retardation syndrome corrected in mice
12-19-2007 · EurekAlert!
Researchers working with mice have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single gene, countering the effects of the fragile X mutation. They said their achievement offers the potential for treatment of the disorder, the most common form of inherited mental retardation and a leading identified genetic cause of autism. There is currently no treatment or therapy for fragile X syndrome, whose symptoms include mental retardation, epilepsy and abnormal body growth.
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- First autism prevention study launched by University of Washington
01-02-2008 · EurekAlert!
Autism researchers at the University of Washington will take the initial step in attempting to prevention the developmental disorder when they launch an $11.3 million study this week.
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- Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
01-08-2008 · EurekAlert!
Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients.
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- Gene tied to longevity also preserves ability to think clearly
12-25-2006 · EurekAlert!
A gene variant linked to living a very long life -- to 90 and beyond -- also serves to help very old people think clearly and retain their memories, according to new research by scientists at the Albert Einstein College of Medicine of Yeshiva University.
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- Brain Regions Do Not Communicate Efficiently In Adults With Autism
10-15-2006 · ScienceDaily
A novel look at the brains of adults with autism has provided new evidence that various brain regions of people with the developmental disorder do not communicate with each other as efficiently as they do in other people.
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- Gene variant is associated with brain anatomy, clinical course of ADHD
08-06-2007 · EurekAlert!
A variant of the dopamine receptor gene may be associated with attention-deficit/hyperactivity disorder and with thinner tissue in areas of the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
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- Gene linked to autism in families with more than one affected child
10-17-2006 · EurekAlert!
A version of a gene has been linked to autism in families that have more than one child with the disorder. Inheriting two copies of this version more than doubled a child's risk of developing an autism spectrum disorder. People with autism spectrum disorders were more likely than others to have inherited a tiny variation in the part of the gene that turns it on and off that cuts gene expression by half.
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