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Do acid blockers let microbes reach the colon?
10-21-2006 · Science News OnlineSuppressing stomach acid while taking antibiotics may allow drug-resistant bacteria to colonize the intestines.
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- LIALDA demonstrates prolonged release of mesalamine
10-17-2007 · EurekAlert!
According to a study using a dynamic in vitro gastrointestinal tract system, Shire plc's ulcerative colitis drug LIALDA (mesalamine) demonstrated a delivery system where the majority of the drug's active ingredient, 5-aminosalicyclic acid, is released over a prolonged period in the simulated colon. The colon is the site of inflammation in ulcerative colitis.
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- LIALDA (TM) demonstrates prolonged release of mesalamine
10-17-2007 · EurekAlert!
According to a study using a dynamic in vitro gastrointestinal tract system, Shire plc's ulcerative colitis drug LIALDA (mesalamine) demonstrated a delivery system where the majority of the drug's active ingredient, 5-aminosalicyclic acid, is released over a prolonged period in the simulated colon. The colon is the site of inflammation in ulcerative colitis.
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- Uniform language for describing genes of pathogenic and beneficial microbes
02-28-2007 · EurekAlert!
An international group of scientists has announced a major expansion of a lingua franca used to describe the activities of genes in living organisms. The expansion provides terms that scientists can use to describe the complex events that occur when a pathogenic or beneficial microbe encounters its host. Understanding these events is crucial for developing new interventions for preventing infections by disease-causing microbes while preserving or encouraging the presence of beneficial microbes.
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- Genetic mutation alters response to heart failure drugs
01-02-2007 · EurekAlert!
Drugs known as beta blockers help reduce the heart's workload during heart failure via their action on beta-adrenergic receptors in cardiac cells. However, doctors remain puzzled by the variable responses to beta blockers among patients. Researchers now show that the key to this variation lies in a single amino acid change in the beta1-adrenergic receptor, that may differ from person to person, which alters the receptor's conformation and the receptor's response to certain beta blockers.
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- Scientists expand microbe 'gene language'
03-01-2007 · EurekAlert!
An international group of scientists has expanded the universal language for the genes of both disease-causing and beneficial microbes and their hosts. This expanded "lingua franca," called the Gene Ontology (GO), gives researchers a common set of terms to describe the interactions between a microbe and its host.
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- Folic acid linked to increased cancer rate
11-02-2007 · EurekAlert!
Two recent commentaries appearing in the November issue of Nutrition Reviews find that the introduction of flour fortified with folic acid into common foods was followed by an increase in colon cancer diagnoses in the U.S. and Canada.
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- Taking folic acid does not reduce risk of precancerous colon tumors
06-08-2007 · EurekAlert!
Taking folic acid supplements does not reduce the risk of developing precancerous tumors in the colon and may even increase the risk, a new study has found.
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- Switch Hitters: Antibacterial compounds target new mechanism to kill microbes
01-13-2007 · Science News Online
Recently discovered ribonucleic acid segments, called riboswitches, may become prime targets for new antibacterial drugs.
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- Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
04-12-2007 · EurekAlert!
In a venture once thought to lie outside the reach of science, researchers from Harvard Medical School and Beth Israel Deaconess Medical Center have captured and sequenced tiny pieces of collagen protein from a 68 million-year-old Tyrannosaurus rex. The protein fragments -- seven in all -- appear to most closely match amino acid sequences found in collagen of present day chickens, lending support to a recent and still controversial proposal that birds and dinosaurs are evolutionarily related.
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- LIALDA demonstrates prolonged release of mesalamine in an in vitro study using a simulated colon
10-17-2007 · EurekAlert!
According to a study using a dynamic in vitro gastrointestinal tract system, Shire plc's ulcerative colitis drug LIALDA (mesalamine) demonstrated a delivery system where the majority of the drug's active ingredient, 5-aminosalicyclic acid, is released over a prolonged period in the simulated colon. The colon is the site of inflammation in ulcerative colitis.
Similar news · Read more »