Daily non-political popular news in brief.

Mutation in HNF4A associated with an increase in birthweight and macrosomia

04-02-2007 · EurekAlert!

In a study in the current issue of PLoS Medicine, a mutation in one gene HNF4A, associated with diabetes in the young, has been shown to be associated with an average increase in birthweight of 790g.

Keywords: mutation, hnf4a, associated, birthweight, macrosomia

« Previous | Next »

Similar news on "Mutation in HNF4A associated with an increase in birthweight and macrosomia":

Study finds first-ever genetic animal model of autism
12-08-2007 · EurekAlert!
By introducing a gene mutation in mice, investigators have created what they believe to be the first accurate model of autism not associated with a broader neuropsychiatric syndrome, according to research presented at the American College of Neuropsychopharmacology Annual Meeting.
Similar news · Read more »
Other highlights from the March 21 JNCI
03-20-2007 · EurekAlert!
Also in the March 21 JNCI are a study on the link between fat intake and breast cancer risk, a plant compound that may decrease breast cancer risk, a critique of the use of progression-free survival in cancer clinical trials, and a mutation to a mismatch repair gene that is associated with colorectal cancer.
Similar news · Read more »
Muscle weakness: New mutation identified
06-14-2007 · EurekAlert!
New research, published in the Journal of Physiology, has identified a novel mutation associated with muscle weakness and distal limb deformities. The study demonstrates that muscle weakness experienced by persons with a regulatory protein tropomyosin mutation is directly related to a mechanism by which the mutant tropomyosin modulates contractile speed and force-generation capacity.
Similar news · Read more »
MGH Cancer Center researchers find new gene associated with Wilms tumor
01-04-2007 · EurekAlert!
Researchers at the Massachusetts General Hospital Cancer Center have discovered a novel gene mutation associated with Wilms tumor, the most common pediatric kidney cancer. The newly identified gene is mutated in about 30 percent of cases of Wilms tumor and is located on the sex-determining X chromosome, which means that a single altered copy would be sufficient for tumor formation.
Similar news · Read more »
Varying prevalence among ethnic groups of gene mutation that increases risk of breast cancer
12-25-2007 · EurekAlert!
Among several US racial/ethnic groups examined, Hispanic women were found to have the highest prevalence of the cancer-associated gene mutation BRCA1 at 3.5 percent, with Asian Americans having the lowest prevalence (0.5 percent), according to a study in the Dec. 26 issue of JAMA.
Similar news · Read more »
ChemGenex announces publication confirming activity of Ceflatonin in T315I-Positive CML
06-11-2007 · EurekAlert!
A report in the Nature publication Leukemia confirms the positive clinical activity of ChemGenex's lead compound, Ceflatonin against Gleevec-resistant, chronic myeloid leukemia (CML) associated with the T315I Bcr-Abl mutation. The T315I mutation, which is increasing in incidence, is known to confer resistance to both Gleevec (imatinib mesylate) and second-generation tyrosine kinase inhibitors (dasatinib and nilotinib). Ceflatonin is currently in phase 2/3 registration-directed studies.
Similar news · Read more »
Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!
A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
Similar news · Read more »
Scientists find major susceptibility gene for Crohn's disease
10-26-2006 · EurekAlert!
Researchers report the discovery of a new genetic link to Crohn's disease. Mutations of a gene, which codes for a receptor in a major inflammatory pathway, are strongly associated with Crohn's, they found. Surprisingly, one type of mutation appears to confer significant protection, prioritizing a crucial target for drugs that might better manage Crohn's disease and ulcerative colitis. More than 1 million Americans have Crohn's or colitis, known collectively as inflammatory bowel disease.
Similar news · Read more »
Tamiflu Significantly Reduces The Risk Of Death From Influenza
10-02-2006 · ScienceDaily
Tamiflu (oseltamivir), is effective in reducing the risk of death associated with seasonal influenza in severely ill patients, according to new data. Treatment of infected adults was associated with a 71 percent reduction in mortality. These results demonstrate the importance of the role of antivirals in the management of seasonal influenza and highlights the seriousness and risk of mortality associated with it.
Similar news · Read more »
Racial disparity in breast cancer outcome linked to aggressive tumors
10-23-2006 · EurekAlert!
Malignancies of the breast can be more aggressive and associated with poorer outcome in African-Americans than other races, according to a new study. The study reviewed patient data from two different clinical trial protocols -- to control for healthcare access biases -- and found that African-Americans have tumors with poorer prognostic cellular characteristics and more aggressive clinical presentations, pointing to the possibility that racially influenced tumor biology may contribute to observed racial disparities in breast cancer outcome.
Similar news · Read more »