Daily non-political popular news in brief.
New role for sugars: Research shows connections between sugar modifications in cells and cancer
04-05-2007 · EurekAlert!In a ground-breaking study published in the top journal, Cell, Dr. James Dennis, senior investigator at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, has discovered a new role for sugars on proteins.
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Keywords: role, sugars, research, shows, connections, sugar, modifications, cells, cancer, show, connection, modification, cell
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- Scripps research scientists show protein accelerates breast cancer progression in animal models
06-20-2007 · EurekAlert!
Scientists at the Scripps Research Institute have shown for the first time that a cytokine called pleiotrophin stimulates the progression of breast cancer in both animal and cell culture models. The study, which tested three separate models to determine the role of inappropriate expression of pleiotrophin, found that it produced striking increases in aggressiveness of the breast cancer cells themselves.
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- New class of RNA molecules may be important in human cancer
09-11-2007 · EurekAlert!
New research shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved noncoding RNAs have been considered "junk" by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
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- Role of TRPM8 in the development of prostate cancer
05-17-2007 · EurekAlert!
In normal prostate epithelium, cells coexist in many stages of development-differentiation, and disrupted differentiation and proliferation are major causes of cancer. A new study shows that the endoplasmic reticulum protein TRPM8 (ER-TRPM8) present in human prostate epithelial luminal cancer cells retains it’s function as a calcium release channel, independent of the differentiation state of the cell, and may be an important factor in controlling the growth of prostate cancer cells.
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- Cancer stem cell subpopulation drives metastasis of human pancreatic cancer
09-12-2007 · EurekAlert!
Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer. The research, published by Cell Press in the Sept. issue of the journal Cell Stem Cell, provides insight into the role of CSCs in cancer initiation, progression and metastasis, and suggests new directions for development of more effective therapeutics.
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- Stress may help cancer cells resist treatment, research shows
04-10-2007 · EurekAlert!
Scientists from Wake Forest University School of Medicine are the first to report that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death.
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- 3 proteins may play important role in nerve-cell repair
04-11-2007 · EurekAlert!
Some mature brain cells can grow new extensions when the amount of three particular proteins on their surface increases, a new study shows. The research examined three related receptor proteins, called GPR3, GPR6 and GPR12, on nerve cells in the brains of rats.
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- New research may show why some prostate cancer recurs after treatment
10-11-2007 · EurekAlert!
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within cancer cells, which suggests that cancer cells may develop the capacity to produce their own androgens.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
04-18-2007 · EurekAlert!
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. Increasingly, stem cells are examined as the cause -- and potential target of treatment -- for many, if not all, cancers.
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