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Penn researchers show how nanocylinders deliver medicine better than nanospheres
04-05-2007 · EurekAlert!Researchers at the University of Pennsylvania School of Medicine have discovered a better way to deliver drugs to tumors. By using a cylindrical-shaped carrier they were able sustain delivery of the anticancer drug paclitaxel to an animal model of lung cancer ten times longer than that delivered on spherical-shaped carriers. These findings have implications for drug delivery as well as for better understanding cylinder-shaped viruses like Ebola and H5N1 influenza.
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Keywords: penn, researchers, show, nanocylinders, deliver, medicine, nanospheres, researcher, nanocylinder, nanosphere
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- Penn study suggests new model for testing and discovery of anti-HIV drugs
02-08-2007 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine are the first to show that a mouse protein, whose human equivalent is related to defense against HIV-1, inhibits the infection and spread of a mouse tumor virus. The study provides a new model for the discovery and evaluation of anti-HIV drugs.
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- Penn study finds ICD devices offer heart patients life-saving benefits
04-05-2007 · EurekAlert!
Researchers at the University of Pennsylvania's School of Medicine have discovered that implantable cardioverter-defibrillators (ICDs) -- electric monitoring devices that deliver a lifesaving shock in the event of a cardiac arrest -- help patients with heart problems live longer more active lives. Peter Groeneveld, M.D., M.S., Assistant Professor of General Internal Medicine and his co-authors report their findings in the April 2007 issue of the journal Pacing and Clinical Electrophysiology.
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- Penn study points to new direction for pancreas cell regeneration
04-03-2007 · EurekAlert!
Past studies in tissue culture have suggested that one type of pancreas cell could be coaxed to transform into insulin-producing islet cells. Now, researchers at the University of Pennsylvania School of Medicine have demonstrated that these pancreatic acinar cells do not become insulin-producing cells in an animal model. However, they did show that injured pancreatic cells readily regenerate back into healthy acinar cells, which has implications for treating cancer and inflammation of the pancreas.
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- Testing delays cause severe AIDS complications, Einstein researchers find
11-02-2007 · EurekAlert!
Despite the availability of life-saving antiretroviral treatment, people infected with HIV continue to die and suffer from complications of AIDS, mainly due to delayed diagnosis and initiation of treatment. A researcher at the Albert Einstein College of Medicine of Yeshiva University and colleagues at Yale University have shed light on why this problem persists. They report their findings in the November issue of the journal Medical Care.
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- Vet medicine researcher examines link between cancer, Down syndrome
02-04-2008 · EurekAlert!
There's new hope for breast cancer research, and it's coming from a very unlikely place. Researchers at the Texas A&M University College of Veterinary Medicine & Biomedical Sciences recently published articles in the journals Molecular and Cellular Biology and Carcinogenesis indicating that a protein long suspected to play a role in Down Syndrome may also contribute to treating this devastating disease.
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- Researchers show that veins stiffen as we age
10-31-2006 · EurekAlert!
As if creaking joints and hardening of the arteries weren't bad enough, a research team from the University of Delaware and the Christiana Care Health System has now confirmed that even our veins stiffen as we age.And that physiological change may be an important factor in the development of high blood pressure, or hypertension, which currently affects an estimated 65 million Americans, most of them older adults, according to UD researcher William Farquhar.
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- Non-drug treatments for dementia show promise, experts say
12-19-2006 · EurekAlert!
Memory training and other non-drug treatments may one day help older adults ward off declines in mental function, according to researchers from Wake Forest University School of Medicine in an editorial in the current issue of the Journal of the American Medical Association.
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- Penn scientists engineer small molecules to probe proteins deep inside cell membrane
03-30-2007 · EurekAlert!
To probe the secrets of inaccessible transmembrane proteins, researchers at the University of Pennsylvania School of Medicine have designed peptides that are able to bind to specific inner regions, using computer algorithms, and information from existing protein sequence and structure databases. This study looks at how the binding of these designed peptides affects the crucial first steps in blood clotting.
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- UT medical researcher determines link between foie gras and disease
06-18-2007 · EurekAlert!
Experimental data published today by University of Tennessee Graduate School of Medicine researchers shows a potential link between foie gras consumption and amyloid-related dieases such as Alzheimer's, rheumatoid arthritis and adult onset diabetes.
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- Penn study maps road to cure for inherited eye diseases
06-22-2007 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have identified proteins in the rod and cones of the eye that could lead to the discovery of the genetic causes of a host of inherited eye diseases. The investigators hope to gain a clearer understanding of what goes wrong at the most basic level in these diseases that cause blindness and other disorders.
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