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Jefferson immunology researchers show blood-brain barrier damage could affect MS severity
04-05-2007 · EurekAlert!Immunology researchers at the Kimmel Cancer Center at Jefferson studying a multiple sclerosis (MS)-like disease in mice have shown that the amount of "damage" to the central nervous system’s protective blood-brain barrier -- in essence, opening it -- almost always correlates to the severity of the disease. The findings can be used for testing potential MS therapies and for better understanding the role of the blood-brain barrier in disease processes.
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Keywords: jefferson, immunology, researchers, show, blood-brain, barrier, damage, affect, severity, researcher, blood, brain
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Immunology researchers have shown how a type of bat rabies infection can be prevented in mice -- even after the virus reaches the brain, when it is most lethal. They found that by opening the central nervous system's (CNS) protective blood-brain barrier, powerful infection fighting substances can swarm in, essentially driving off the invading virus. A better understanding of the process, they say, may lead to improved treatment for late-stage rabies infections in humans.
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- Vasectomy may put men at risk for type of dementia
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- The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease
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A team of international scientists, including a Saint Louis University researcher, demystifies the blood-brain barrier in an article in the Lancet Neurology.
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- New neuroimaging study identifies 'brain signature' for cigarette cravings
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A new brain imaging study by researchers in the Abramson Cancer Center of the University of Pennsylvania shows that cigarette cravings in smokers who are deprived of nicotine are linked with increased activation in specific regions of the brain. Using a novel method of measuring brain blood flow developed at Penn, this study is the first to show how abstinence from nicotine produces brain activation patterns that relate to urges to smoke.
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