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Not-So-Artful Dodgers: Countering drug tests with niacin proves dangerous
04-07-2007 · Science News OnlineAttempts to cleanse illicit drugs from one's body by taking large doses of niacin can cause life-threatening reactions.
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- DNA-damage test could aid drug development
05-14-2007 · EurekAlert!
Researchers from Massachusetts Institute of Technology and Whitehead Institute have developed a cell culture test for assessing a compound's genetic toxicity that may prove dramatically cheaper than existing animal tests. This assay would allow genetic toxicity to be examined far earlier in the drug development process, making it much more efficient.
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- Misusing vitamin to foil drug test may be toxic; plus, it doesn't work
04-10-2007 · EurekAlert!
Taking excessive doses of a common vitamin in an attempt to defeat drug screening tests may send the user to the hospital -- or worse. Researchers in Philadelphia reported on two adults and two adolescents who suffered toxic side effects from taking large amounts of niacin, also known as vitamin B3, in mistaken attempts to foil urine drug tests.
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- Mouse tests predict drug response in relapsing pancreatic cancer patients
10-11-2006 · EurekAlert!
By slicing up bits of patient tumors and grafting them into mice, Johns Hopkins Kimmel Cancer Center specialists have figured out how to accurately "test drive" chemotherapy drugs to learn in advance which drug treatments offer each individual pancreatic cancer patient the best therapeutic journey.
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- Sports cheats beware -- new test detects previously undetectable drug
11-12-2006 · EurekAlert!
Injecting performance enhancing corticosteroid hormones for other than medical treatment is banned, and tests exist that can detect injected hormones. Injecting synacthen, which stimulates the body to produce extra amounts of its own corticosteroid hormones is also banned. But until now there has been no test that could detect it in a blood sample.
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- 'Modular' leukemia drug shows promise in early testing
06-28-2007 · EurekAlert!
A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows. The agent represents a new class of agents called small modular immunopharmaceuticals. Called CD37-SMIP, the agent targets a protein called CD37 on the surface of these leukemia cells.
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- Mouse Tests Predict Drug Response In Relapsing Pancreatic Cancer Patients
10-12-2006 · ScienceDaily
By slicing up bits of patient tumors and grafting them into mice, Johns Hopkins Kimmel Cancer Center specialists have figured out how to accurately 'test drive' chemotherapy drugs to learn in advance which drug treatments offer each individual pancreatic cancer patient the best therapeutic journey.
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- Quick microchip test for dangerous antibiotic resistant bacteria
09-04-2007 · EurekAlert!
Researchers at the Veterinary Laboratories Agency in Surrey have developed microchips capable of quickly and cheaply identifying dangerous and drug resistant bacteria in clinical samples, scientists announced today, Sept. 5, 2007, at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs Sept. 3-6, 2007.
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- Colon cancer screening -- Going 'Back To The Future'?
02-19-2007 · EurekAlert!
In an editorial in the February 20 edition of the Annals of Internal Medicine, Indiana University School of Medicine gastroenterologist and Regenstrief Institute, Inc. researcher Thomas Imperiale, M.D., writes that to increase screening rates for colorectal cancers, we need more convenient and less invasive screening tests. An infrequently used type of fecal sampling test, which has had Federal Drug Administration approval since 2001, may meet that need he says.
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- UNC study questions FDA genetic-screening guidelines for cancer drug
08-28-2007 · EurekAlert!
Not everyone needs a genetic test before taking the cancer drug irinotecan, and the US Food and Drug Administration should modify its prescription guidelines to say so, according to researchers at the University of North Carolina at Chapel Hill.
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- New strategy to cut heart attack risk is effective in initial test
12-17-2007 · EurekAlert!
The first clinical trial of a new kind of drug to cut the risk of cardiovascular disease has been found safe and effective at dropping levels of "bad" low density lipoprotein cholesterol by as much as 40 percent. High LDL levels increase the risk for heart attack and stroke.
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