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Stress may help cancer cells resist treatment, research shows
04-10-2007 · EurekAlert!Scientists from Wake Forest University School of Medicine are the first to report that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death.
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Keywords: stress, cancer, cells, resist, treatment, research, shows, cell, show
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- New research may show why some prostate cancer recurs after treatment
10-11-2007 · EurekAlert!
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within cancer cells, which suggests that cancer cells may develop the capacity to produce their own androgens.
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- Scientists follow familiar TRAIL to new cancer therapy
07-09-2007 · EurekAlert!
A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials. The research, published in the July issue of the journal Cancer Cell, published by Cell Press, provides a pharmacological method for enhancing the potency and effectiveness of a tumor necrosis factor death receptor ligand against a variety of human cancers.
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- Custom-made cancer cell attacks
02-16-2007 · EurekAlert!
Imagine a cancer treatment tailored to the cells in a patient’s body, each person receiving a unique treatment program. This is what Natural Sciences and Engineering Research Council grantee Thomas Ruth and his colleagues hope to accomplish within the next decade. Using the TRIUMF particle accelerator based in Vancouver, British Columbia, they are taking vast amounts of radioactive material and separating the particular atoms they need for therapy
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- Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway
06-11-2007 · EurekAlert!
Using a functional genomic screen, scientists have defined elements that impact the responsiveness of cancer cells to drugs commonly used as anticancer therapeutics. The research, published in the June issue of the journal Cancer Cell, published by Cell Press, identifies individual genes that are associated with resistance to chemotherapeutic drugs, and sets the stage for future studies that may significantly enhance the ability to predict whether or not a particular tumor will respond to treatment.
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- Impaired Gene Helps Nonsmall-cell Lung Cancer Resist Drug
10-02-2006 · ScienceDaily
Lung cancer cells with a defective version of a potential tumor suppressor gene are highly resistant to attack by a platinum-based drug commonly used to treat the disease, researchers at the University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center at Dallas report in the cover article of the Oct. 1 edition of Cancer Research.
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- New role for sugars: Research shows connections between sugar modifications in cells and cancer
04-05-2007 · EurekAlert!
In a ground-breaking study published in the top journal, Cell, Dr. James Dennis, senior investigator at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, has discovered a new role for sugars on proteins.
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- Scripps research scientists show protein accelerates breast cancer progression in animal models
06-20-2007 · EurekAlert!
Scientists at the Scripps Research Institute have shown for the first time that a cytokine called pleiotrophin stimulates the progression of breast cancer in both animal and cell culture models. The study, which tested three separate models to determine the role of inappropriate expression of pleiotrophin, found that it produced striking increases in aggressiveness of the breast cancer cells themselves.
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- New class of RNA molecules may be important in human cancer
09-11-2007 · EurekAlert!
New research shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved noncoding RNAs have been considered "junk" by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
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- New drug therapy to combat GVHD in stem-cell patients shows significant reduction in deaths
01-23-2007 · EurekAlert!
Gastrointestinal graft-vs.-host disease is a common and potentially deadly side effect for patients who undergo an allogeneic stem-cell transplant to treat certain blood cancers. Now, new research from Fred Hutchinson Cancer Research Center shows that adding a widely used topical corticosteroid to the standard treatment for GVHD kept the disease in remission and significantly reduces deaths one year after therapy.
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- Novel MS drug shows promise in 2 lethal leukemias
08-28-2007 · EurekAlert!
A new study suggests that an experimental drug being tested for the treatment of multiple sclerosis and to prevent organ rejection might also help people with certain deadly forms of chronic and acute leukemia. The laboratory and animal study focused on the drug, called fingolimod. Researchers said it might help patients with advanced chronic myelogenous leukemia or acute lymphocytic leukemia, and whose cancer cells show a particular genetic change called the Philadelphia chromosome.
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