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New lab mice pave way for novel studies of human infections
10-23-2006 · UT Southwestern Medical CenterA new type of laboratory mouse developed at UT Southwestern Medical Center can fight certain infections the same way humans do, making the rodents very useful for novel studies of human-pathogen interaction and developing disease therapies.
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Keywords: lab, mice, pave, way, novel, studies, human, infections, study, infection
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- New lab mice pave way for novel studies of human infection
10-22-2006 · EurekAlert!
A new type of laboratory mouse developed at UT Southwestern Medical Center can fight certain infections the same way humans do, making the rodents very useful for novel studies of human-pathogen interaction and developing disease therapies.
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- Genetic 'roadblock' hoped to inspire future type 2 diabetes research
10-02-2007 · EurekAlert!
A team of Mount Sinai Hospital researchers has found that a 'genetic roadblock' identified in a recent study could pave the way toward novel treatments for type 2 diabetes. In the study, researchers from the Samuel Lunenfeld Research Institute of Mount Sinai Hospital found the first genetic evidence that the elimination of the gene for glycogen synthase kinase-3 in mice sensitizes the animals to insulin.
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- Tips from the Journals of the American Society for Microbiology
08-20-2007 · EurekAlert!
In this issue: "Phage Therapy May Control Staph Infections in Humans Including MRSA"; "New Smallpox Vaccine Candidates Demonstrate Superior Immune Response, Efficacy and Safety in Mice"; and "First Animal Model Developed for Oral Infection of Human Poliovirus."
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- Major Advance In The Fight Against Chronic Virus Infections
10-11-2006 · ScienceDaily
A major finding that could lead to a new approach for treating hepatitis C and other chronic virus infections was announced today by researchers at the La Jolla Institute for Allergy and Immunology. The research team, using controlled laboratory studies of mice, was able to eliminate a chronic virus infection in the animals by blocking a key messenger molecule in the immune system. The finding has particular relevance for hepatitis C, but may also be applicable to AIDS, cytomegalovirus and other chronic virus infections.
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- Stanford researchers identify immune dysfunction in melanoma patients
05-07-2007 · EurekAlert!
Researchers at Stanford have begun to shed light on why the human immune system isn't able to stop such cancers as melanoma, suggesting answers that could pave the way for better treatment of this often-fatal illness. In a small study, the scientists found that the immune cells in a majority of people with this deadly skin cancer fail to respond properly to a molecule called interferon, which normally activates the immune system.
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- Altering a protein makes mice less fearful
08-01-2007 · EurekAlert!
A University of Iowa study shows that loss or chemical inhibition of a protein, known as acid sensing ion channel protein, reduces innate fear behavior in lab animals, making normally timid mice relatively fearless. The findings might provide useful insight into anxiety disorders, and may even point the way to a new therapeutic target.
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- Dietary copper may ease heart disease
03-05-2007 · EurekAlert!
Including more copper in your everyday diet could be good for your heart, according to scientists at the University of Louisville Medical Center and the USDA Human Nutrition Research Center. Their studies show that giving copper supplements to mice eased the stress on their over-worked hearts by preventing heart enlargement. The study will be published online on March 5 in the Journal of Experimental Medicine.
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- Regulatory T cells require WASp if they are to prevent self-destruction
01-11-2007 · EurekAlert!
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity. Most studies have focused on understanding how WASp deficiency causes defects in T cell activation, but a new study shows that in mice and humans a population of T cells known as regulatory T cells, which prevent other immune cells attacking the body's and causing autoimmunity, are also impaired in the absence of WASp.
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- Parasite infection may benefit MS patients
01-17-2007 · EurekAlert!
The first study examining the relationship between parasite infections and MS in humans suggests that such infections may affect the immune response in a way that alters the course of MS.
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- A new approach to study flu drug resistance
12-06-2007 · EurekAlert!
Researchers have created a new approach for studying resistance to Neuraminidase Inhibitors in influenza. The study, published Dec. 7 in PLoS Computational Biology, combines data from influenza infections of human volunteers with a mathematical model which estimates the expected number of newly generated resistant infections. This new approach provides a more meaningful assessment of the danger of drug resistance emergence, compared to the current way of reporting the fraction/number of resistant cases.
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