Daily non-political popular news in brief.
Genes set scene for metastasis
04-11-2007 · EurekAlert!Biologists at Memorial Sloan-Kettering Cancer Center have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights targets for therapeutic treatment.
Read more »
Keywords: genes, set, scene, metastasis, gene, metastasi
« Previous | Next »
Similar news on "Genes set scene for metastasis":
- Scientists expand microbe 'gene language'
03-01-2007 · EurekAlert!
An international group of scientists has expanded the universal language for the genes of both disease-causing and beneficial microbes and their hosts. This expanded "lingua franca," called the Gene Ontology (GO), gives researchers a common set of terms to describe the interactions between a microbe and its host.
Similar news · Read more »
- Autism Consortium releases data on genes involved in autism to researchers worldwide
10-22-2007 · EurekAlert!
The Autism Consortium, a group of researchers, clinicians and families dedicated to accelerating research and enhancing clinical care for autism, announced today that it has completed the first genome scan for Autism Spectrum Disorders through its Autism Gene Discovery Project and released the reference data set to a database that autism researchers around the world can use. The scan was conducted on genetic data from more than 3,000 children with ASD and their families.
Similar news · Read more »
- Plants, plasmids and possibilities -- Methods permit functional gene studies in plants
12-01-2006 · EurekAlert!
Decaffeinated coffee plants, pest-resistant cotton, and Vitamin A-producing rice varieties have all been developed by introducing genes into plants. Scientists also create modified plants to identify and characterize the functions of specific genes. The current issue of Cold Spring Harbor Protocols -- released online today -- includes a set of techniques for the creation of transgenic plants.
Similar news · Read more »
- AVN944 inhibits IMPDH & induces apoptosis-related biomarkers in patients with hematologic cancers
12-11-2006 · EurekAlert!
IMPDH is highly upregulated in most hematological cancers and solid tumors -- an essential role in cancer cell synthesis of DNA and RNA. Inhibition of IMPDH represents a new and important approach to treat cancer. In a Phase I trial of AVN944, AvalonRx identified a set of 34 genes. These gene markers correlate with the biochemical effects of AVN944 on protein function -- believed to result in tumor cell apoptosis at the right doses.
Similar news · Read more »
- AVN944 inhibits IMPDH and induces apoptosis-related biomarkers in patients with hematologic cancers
12-11-2006 · EurekAlert!
IMPDH is highly upregulated in most hematological cancers and solid tumors -- an essential role in cancer cell synthesis of DNA and RNA. Inhibition of IMPDH represents a new and important approach to treat cancer. In a Phase I trial of AVN944, AvalonRx identified a set of 34 genes. These gene markers correlate with the biochemical effects of AVN944 on protein function -- believed to result in tumor cell apoptosis at the right doses.
Similar news · Read more »
- Bits of 'junk' RNA aid master tumor-suppressor gene
08-23-2007 · EurekAlert!
A University of Michigan study reveals that the p53 gene, a key protector mutated in half of all cancers, gets help in its vital job of stifling tumors from a trio of little-known micro RNA genes. Drugs that mimic their benefits could become important tools in cancer therapy someday.
Similar news · Read more »
- High and mighty: first common height gene identified by researchers behind 'obesity gene' finding
09-02-2007 · EurekAlert!
Whilst we all know that tall parents are more likely to have tall children, scientists have been unable to identify any common genes that make people taller than others. Now, however, scientists have identified the first gene, known as HMGA2, a common variant of which directly influences height.
Similar news · Read more »
- Mechanism for the in-vivo transport of siRNA
09-17-2007 · EurekAlert!
RNA interference, a natural mechanism that inhibits the gene expression of individual genes in eukaryotic cells, is a major topic in modern biology. However, their potential was usable to only a limited extent in mammals because the mechanism for the uptake of small RNAs was unknown up to now. ETH Zurich biologists have now clarified this, which also opens the door for therapies based on this mechanism.
Similar news · Read more »
- Tolerance to inhalants may be caused by changes in gene expression
10-17-2007 · EurekAlert!
Changes in the expression of genes may be the reason why people who abuse inhalants, such as spray paint or glue, quickly develop a tolerance, biologists at The University of Texas at Austin have discovered.
Similar news · Read more »
- International team compares 12 fruit fly genomes
11-08-2007 · EurekAlert!
Cornell University researchers have played a major role in an international scientific team that has compared the complete set of genes of 12 closely related fruit fly species. As well has having implications for human health, the analysis paves the way for better understanding the evolution of each species.
Similar news · Read more »