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Early-stage sperm cells created from human bone marrow

04-12-2007 · EurekAlert!

Adult stem cells extracted from human bone marrow have been coaxed into becoming male reproductive cells.

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Keywords: early-stage, sperm, cells, created, human, bone, marrow, early, stage, cell

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  1. First human trial tests stem-cell-based treatment for heart attacks
    03-25-2007 · EurekAlert!
    Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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  2. Type of stem cell found to reside in transplanted lungs
    03-08-2007 · EurekAlert!
    A new study involving a type of stem cells from the lungs of transplant patients demonstrates for the first time that these progenitor cells reside in adult organs and are not derived from bone marrow, which leads to the possibility that the cells may be able to help with the rejection of donated organs and with various kinds of lung disease.
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  3. Can you hear me now? Stem cells enhance hearing recovery
    06-25-2007 · EurekAlert!
    Researchers have shown that bone marrow stem cells injected into a damaged inner ear can speed hearing recovery after partial hearing loss. The related report by Kamiya et al, "Mesenchymal stem cell transplantation accelerates hearing recovery through the repair of injured cochlear fibrocytes," appears in the July issue of The American Journal of Pathology.
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  4. Adult stem cell application effective in treatment of peripheric vascular disease
    01-24-2008 · EurekAlert!
    Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.
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  5. Bone marrow microenvironment can contribute to blood cell disorder
    06-14-2007 · EurekAlert!
    Disorders of blood cells may begin in the biological environment where the cells develop, not just with the cells themselves, according to a study from researchers at the Massachusetts General Hospital and the Peter MacCallum Cancer Center in Melbourne, Australia.
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  6. Stroke victims may benefit from stem cell transplants
    01-28-2008 · EurekAlert!
    Two studies published in the current issue of Cell Transplantation examine the potential for cell transplants to benefit stroke victims. When injected into animal models and tracked via chemical tags and imaging, mensenchymal stem cells in one study, and bone marrow stromal cells in a second study, migrated within one to two weeks to affected brain areas and became therapeutically active. Both studies suggest that novel stem cell therapies can be developed.
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  7. Not all embryonic stem cell lines are created equal
    08-06-2007 · EurekAlert!
    When it comes to generating neurons, researchers have found that not all embryonic stem cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation -- which have yet to be identified -- can influence the developmental properties of human ES cells.
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  8. How to grow muscle cells in a dish
    11-09-2006 · EurekAlert!
    Smooth muscle cells (SMCs) are a crucial component of many parts of the body, including blood vessels. A new study shows that fully functional SMCs can be generated from multipotent adult progenitor cells (MAPCs) from rat, mouse, pig and human bone marrow using only the soluble factor TGF-beta or TGF-beta and PDGFB. SMCs generated this way could provide a source of SMCs for engineering tissues, for example new blood vessels for use in bypass surgery.
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  9. University of Pittsburgh researchers culture blood-forming stem cells from human fat tissue
    06-14-2007 · EurekAlert!
    Researchers at the University of Pittsburgh School of Medicine have successfully isolated and cultured human hematopoietic stem cells from fat, or adipose, tissue. Since it has been shown in some cases that tumor cells contaminating bone marrow grafts are the source of recurrent malignancies after autologous transplantation, this may be another important source of cells for reconstituting the bone marrow of patients undergoing intensive radiation therapy for blood cancers.
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  10. Pittsburgh-based team engineers muscle, bone cell differentiation with aid of ink-jet printer
    12-10-2006 · EurekAlert!
    A team of researchers from Carnegie Mellon University and the University of Pittsburgh has created and used an innovative ink-jet system to print "bio-ink" patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells. The results, which could revolutionize the design of replacement body tissues, will be presented Sunday, Dec. 10 at the 46th annual meeting of the American Society for Cell Biology in San Diego.
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