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Johns Hopkins develops pancreas cancer risk model
04-16-2007 · EurekAlert!People with a family history of pancreas cancer now have a way to accurately predict their chance of carrying a gene for hereditary pancreas cancer and their lifetime risk of developing the disease. Developed by Johns Hopkins Kimmel Cancer Center researchers, the novel computer software tool is designed to help genetic counselors and physicians decide who would most benefit from early screening.
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- Keeping at-risk cells from developing cancer
12-10-2007 · EurekAlert!
Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes -- in this case the inappropriate activation of a normally silent gene -- develop by becoming addicted to certain growth factors. Reporting online in next week's Early Edition of the Proceedings of the National Academies of Sciences, the team shows that blocking this "addiction" can greatly prevent cancer growth.
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- Gene markers located for hereditary prostate cancer
01-16-2008 · EurekAlert!
Researchers at the Johns Hopkins Brady Urological Institute, Wake Forest University and the Karolinska Institute in Sweden have identified an array of gene markers for hereditary prostate cancer that, along with family history for the disease, appear to raise risk to more than nine times that of men without such markers. The panel, gleaned from a study of more than 4,000 Swedes, found that these markers are common and could account for nearly half of the prostate cancer cases in this study.
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- HPV infection linked to throat cancers
05-09-2007 · EurekAlert!
Researchers at the Johns Hopkins Kimmel Cancer Center have conclusive evidence that human papillomavirus (HPV) causes some throat cancers in both men and women. Reporting in the May 10 issue of the New England Journal of Medicine, the researchers found that oral HPV infection is the strongest risk factor for the disease, regardless of tobacco and alcohol use, and having multiple oral sex partners tops the list of sex practices that boost risk for the HPV-linked cancer.
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- 'Swish-and-spit' test accurate for cancer
01-01-2008 · EurekAlert!
A morning gargle could someday be more than a breath freshener -- it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.
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- Cancer risks for urban African-American women grow, healthy diets more difficult to maintain
11-28-2007 · EurekAlert!
Women living in the inner city have difficulty meeting dietary goals that could help prevent cancer, according to a report from Johns Hopkins University researchers. In a study of African-American women living in public housing within Washington, DC, the researchers found that the majority met one -- or none -- of five dietary goals suggested to reduce the risk of developing cancer. In particular, these women were unlikely to eat a healthy diet that included the recommended amount of fresh fruits and vegetables.
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- Colon cancer proteins show promise for blood test
06-15-2007 · EurekAlert!
Searching for less invasive screening tests for cancer, Johns Hopkinsscientists have discovered proteins present in blood that accuratelyidentify colon cancer and precancerous polyps.Initial studies of the proteins, CCSA-3 and CCSA-4, suggest they couldbe used to develop a blood test to identify at-risk individuals.
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- Study finds gene linked to aggressive prostate cancer
12-11-2007 · EurekAlert!
Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive prostate cancer. Research teams from the Translational Genomics Research Institute, Wake Forest University School of Medicine, the Karolinska Institute in Stockholm, Sweden, and Johns Hopkins Medical Institutions made the discovery jointly.
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- Hopkins team develops first mouse model of schizophrenia
07-30-2007 · EurekAlert!
Johns Hopkins researchers have genetically engineered the first mouse that models both the anatomical and behavioral defects of schizophrenia, a complex and debilitating brain disorder that affects over 2 million Americans.
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- Biomarkers predict risk for invasive breast cancer years before the tumor develops
11-12-2007 · EurekAlert!
A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer. The research, published by Cell Press in the November issue of Cancer Cell, provides critical information that can be used to determine whether a woman should receive more or less aggressive therapy.
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- Gene dose affects tumor growth
01-03-2008 · EurekAlert!
Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth.
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