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Brain networks strengthened by closing ion channels
04-20-2007 · EurekAlert!Yale School of Medicine and University of Crete School of Medicine researchers report in Cell April 20 the first evidence of a molecular mechanism that dynamically alters the strength of higher brain network connections involved in working memory. This discovery may help the development of drug therapies for the cognitive deficits of normal aging, and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder (ADHD).
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Keywords: brain, networks, strengthened, closing, ion, channels, network, channel
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Similar news on "Brain networks strengthened by closing ion channels":
- Brain networks strengthened by closing ion channels
04-20-2007 · EurekAlert!
Yale School of Medicine and University of Crete School of Medicine researchers report in Cell April 20 the first evidence of a molecular mechanism that dynamically alters the strength of higher brain network connections.
Similar news · Read more »
- Revolution in understanding of ion channel regulation
01-30-2008 · EurekAlert!
A study at Rush University Medical Center in Chicago published this week in the online version of Biophysical Journal proposes that bubbles may control the opening and closing of ion channels. This new understanding of the channels that control much of life in health and disease provides a vital piece of the molecular puzzle.
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- Brain network related to intelligence identified
09-11-2007 · EurekAlert!
Researchers have uncovered evidence of a distinct neurobiology of human intelligence. This Parieto-Frontal Integration Theory identifies a network related to intelligence, one primarily involving areas in the frontal and the parietal lobes. The data suggest that some of the brain areas related to intelligence are the same areas related to attention, memory and language. This possible integration of cognitive functions suggests that intelligence levels might be based on how efficient the frontal-parietal networks process information.
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- New insight into the mechanisms of voltage sensing and transduction in biological processes
09-14-2007 · EurekAlert!
The voltage sensor of voltage-gated ion channels is a conserved protein domain that senses millivolt changes in transmembrane potential, to regulate ion permeation through the channel. A recently discovered protein, Ci-VSP, has a voltage sensor that is coupled not to an ion channel but to a phosphatidylinositide phosphosphatase, the activity of which depends on membrane potential.
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- Scientists identify 2 distinct Parkinson's networks
07-09-2007 · EurekAlert!
Parkinson's that causes tremors, rigidity and slowed movements also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks. David Eidelberg, MD, head of the Center for Neurosciences at the Feinstein Institute for Medical Research, and his colleagues measured and quantified this network of brain regions during a five-year study of newly diagnosed Parkinson's patients who agreed to be followed several times over the course of the study.
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- JCI online early table of contents: Jan. 2, 2008
01-02-2008 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Jan. 2, 2008, in the JCI, including: Il-22 gene delivers the goods and decreases intestinal inflammation; Epilepsy and brain pathology linked together by the protein ADK; Softly, softly: Phex gene mutation in mouse bone cells causes rickets; Lidocaine can really get on your nerves: Local anesthetics interact with the ion channel TRVP1 on neurons; and others.
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- Altered sodium channel function linked to heart failure
11-22-2006 · EurekAlert!
The results of a new study using mice and heart muscle cells from rabbits have provided a potential molecular explanation for the abnormally rapid heartbeats known as ventricular tachyarrhythmias (VTs) that can cause the sudden death associated with heart failure. Researchers from Georg-August-University Gцttingen, Germany, show that overexpression of CaMKII alters the function of channels that regulate sodium ion influx into heart muscle cells, something that has been linked with VTs in genetically susceptible individuals.
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- Complex channels
01-24-2007 · EurekAlert!
The messages passed in a neuronal network can target something like 100 billion nerve cells in the brain alone. These, in turn, communicate with millions of other cells and organs in the body. A team at the Weizmann Institute has now shed light on this mysterious mechanism. The discovery could have important implications for the future development of drugs for epilepsy and other nervous system diseases.
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- Role of noise in neurons
05-03-2007 · EurekAlert!
Addressing a current issue in neuroscience, Aldo Faisal and Simon Laughlin from Cambridge University investigate the reliability of thin axons for transmitting information. They show that noise effects in ion channels in the brain are much larger than previously assumed -- meaning the fidelity of transmission is compromised.
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- Bacterial toxin closes gate on immune response, Penn researchers discover
02-13-2008 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have demonstrated that a bacterial toxin from the common bacterium Staphylococcus aureus shuts down the control mechanism of the tunnel, called an ion channel, in immune cell membranes. Shutting down ion channels has long been known to suppress the immune response, and the bacteria may use the toxin to neutralize host defenses against bacteria.
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