Daily non-political popular news in brief.

Knocking out survival protein could aid leukemia treatment

An effective way to fight leukemia might be to knock out a specific protein that protects cancer cells from dying, a new study shows. The findings suggest that a drug that can block this "survival protein" might on its own be an effective therapy.

Read more »

Keywords: knocking, survival, protein, aid, leukemia, treatment

« Previous | Next »

Similar news on "Knocking out survival protein could aid leukemia treatment":

1. JCI table of contents -- March 8, 2006
   03-08-2007 · EurekAlert!
   This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, March 8, 2006, in the JCI, including: Therapeutic peptide frees the protein p73 to kill tumor cells; CDX2: a protein that promotes leukemia; Mesenchymal stem cells are long-term tissue residents; SPDEF makes the lungs more “asthma-like”; and SHIP1 in platelets practices first aid.
   Similar news · Read more »
   
2. Human C-reactive protein regulates myeloma tumor cell growth and survival
   09-10-2007 · EurekAlert!
   Scientists report that a protein best known as a common marker of inflammation plays a key role in the progression of human cancer. The research, published by Cell Press in the September issue of the journal Cancer Cell, implicates C-reactive protein (CRP) as a potential target for cancer treatment.
   Similar news · Read more »
   
3. CDX2 -- A protein that promotes leukemia
   03-07-2007 · EurekAlert!
   Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells and that CDX2 has a causal role in the pathogenesis of AML. CDX2 regulates the expression of a number of genes that encode members of the HOX family of proteins, which might provide a new set of targets for the treatment of individuals with AML.
   Similar news · Read more »
   
4. Other highlights in the May 16 JNCI
   05-15-2007 · EurekAlert!
   Also in the May 16 JNCI is a study linking moderate drinking and renal cell cancer, second cancers in childhood leukemia and lymphoma survivors, a study that finds no connection between clodronate and prostate cancer survival, and a protein that may prevent cancer cells from dying.
   Similar news · Read more »
   
5. Potential New Target For Leukemia Treatment
   10-10-2006 · ScienceDaily
   Cincinnati Children's Hospital Medical Center researchers have identified the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia. The paper is due to appear in an upcoming edition of the journal, Nature Immunology.
   Similar news · Read more »
   
6. Research shows survival benefit for leukemia patients treated with arsenic trioxide
   06-04-2007 · EurekAlert!
   Through participation in a government-sponsored multi-year study, researchers at the Comprehensive Cancer Center at Wake Forest University have helped confirm that arsenic trioxide -- marketed as Trisenox -- significantly improves patient survival when coupled with standard chemotherapy treatment in newly diagnosed patients with acute promyelocytic leukemia, or APL.
   Similar news · Read more »
   
7. Drug blocks lethal motor-neuron disease in mice
   02-22-2007 · EurekAlert!
   Spinal muscular atrophy (SMA) is a motor-neuron disease caused by mutations in the gene SMN1 that prevent it producing the protein SMN. New research shows that in a lethal mouse model of SMA the drug trichostatin A (TSA), which is a hydroxamic acid HDAC inhibitor, can improve survival and attenuate disease, indicating that hydroxamic acid HDAC inhibitors might be potential therapeutics for the treatment of individuals with SMA.
   Similar news · Read more »
   
8. SUMO wrestles SENP1 over response to hypoxia, providing possible cancer targets
   11-01-2007 · EurekAlert!
   Researchers at the University of Texas M. D. Anderson Cancer Center have found a protein that enables cellular survival during periods of low oxygen, or hypoxia, which also is key for development of many kinds of cancer.
   Similar news · Read more »
   
9. Treatment extends survival in mouse model of spinal muscular atrophy
   02-22-2007 · EurekAlert!
   Drug therapy can extend survival and improve movement in a mouse model of spinal muscular atrophy (SMA), new research shows. The study, carried out at the NIH's National Institute of Neurological Disorders and Stroke (NINDS), suggests that similar drugs might one day be useful for treating human SMA.
   Similar news · Read more »
   
10. Colon cancer survival linked to number of lymph nodes examined
    03-20-2007 · EurekAlert!
    An analysis of 17 studies from nine countries has found that the more lymph nodes that are removed and examined during surgical treatment of colon cancer, the better the outcome appears to be for patients. The study suggests that removal of the nodes takes away a reservoir for potentially lethal cancer, and that knowing how far a cancer has spread leads to tailored and more beneficial treatment, according to researchers at the University of Texas M. D. Anderson Cancer Center.
    Similar news · Read more »