Daily non-political popular news in brief.
Deactivating protein may protect nerve fibers in MS
04-23-2007 · EurekAlert!Oregon Health & Science University neuroscientists are eyeing a protein as a potential therapeutic target for multiple sclerosis because de-activating it protects nerve fibers from damage. OHSU researchers have shown that genetically inactivating a protein called cyclophilin D can protect nerve fibers in a mouse model of multiple sclerosis. Cyclophin D is a key regulator of molecular processes in the nerve cell's powerhouse, the mitochondrion, and can participate in nerve fiber death.
Read more »
Keywords: deactivating, protein, protect, nerve, fibers, fiber
« Previous | Next »
Similar news on "Deactivating protein may protect nerve fibers in MS":
- Cold feeling traced to source
12-18-2007 · EurekAlert!
For the first time, neuroscientists have visualized cold fibers -- strands reaching from sensory neurons near the spinal cord to nerve endings in the skin tuned to sense different types of cold. The study confirms the important role of the protein TRMP8 in cold-sensing neurons.
Similar news · Read more »
- Targeting tau: Inflammation study suggests new approach for fighting Alzheimer's
02-01-2007 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have shown that impaired function and loss of synapses in the hippocampus of a mouse form of Alzheimer's disease (AD) is related to the activation of immune cells called microglia, which cause inflammation. These events precede the formation of tangles -- twisted fibers of tau protein that build up inside nerve cells -- a hallmark of advanced AD.
Similar news · Read more »
- Waste not, want not: Role for caveolin-3 in muscular dystrophy
10-12-2006 · EurekAlert!
Muscular dystrophies are characterized by skeletal muscle weakness due to muscle fiber wasting and loss. Kawasaki Medical School researchers now show in the JCI that mice lacking caveolin-3 -- a protein that helps form a scaffold onto which other signaling molecules assemble at the cell plasma membrane -- increases the intracellular activity of myostatin, an inhibitor of muscle growth, and leads to muscle wasting. Myostatin inhibition may have potential as a therapy for certain muscular dystrophies.
Similar news · Read more »
- Slow reading in dyslexia tied to disorganized brain tracts
12-03-2007 · EurekAlert!
Researchers at Children's Hospital Boston and Beth Israel Deaconess Medical Center have found that difficulty in reading smoothly, or fluently, which occurs in some types of dyslexia, may be caused by disorganized, meandering tracts of nerve fibers in the brain. The findings, which point to organized white matter as the structural basis in the brain for fluent reading, could help specialists find new ways to improve the automatic nature of reading in individuals with dyslexia.
Similar news · Read more »
- Protein protects against nerve degeneration
11-30-2006 · EurekAlert!
A protein called NMNAT protects against nerve cell degeneration in fruit flies and mice. The finding begs the question if a drug might be developed that could stimulate extra protein production and thus neuronal protection -- both in injured cells and in those degenerating because of disease.
Similar news · Read more »
- Protein found that may provide relief from neuropathic pain
12-04-2007 · EurekAlert!
Research in rodents by scientists from the UC-San Diego School of Medicine has provided evidence that a protein called LRP1 may help to ease neuropathic pain by blocking the response of glial cells that support and protect sensory neurons in the peripheral nervous system. Neuropathic pain is caused by injury to the peripheral nerves in diseases such as HIV/AIDS, shingles, and cancer or in repetitive motion disorders and trauma, and does not respond well to conventional pain-relieving drugs.
Similar news · Read more »
- Cause of nerve fiber damage in multiple sclerosis identified
10-16-2006 · EurekAlert!
Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease.
Similar news · Read more »
- Weizmann Institute scientists discover a key player in embryonic muscle development
04-11-2007 · EurekAlert!
In the final stage of muscle fiber development, the cell membranes of attached myoblasts open up and fuse together, forming one large, unified cell. It is known how myoblasts identify other myoblasts and cling together, but the way that the cell membranes fuse into one has remained a mystery. Scientists have now discovered that a protein called WIP plays a key role in muscle cell fusion.
Similar news · Read more »
- Nerve fibers need specific growth factor chemical to form connections within the brain
11-17-2006 · EurekAlert!
A discovery on how neural circuitry develops to aid proper cerebral cortex activity may help explain the memory and cognitive decline seen in Alzheimer's disease patients -- a discovery that could point toward potential treatments, according to UC Irvine scientists.
Similar news · Read more »
- Researchers find 'zip code' spurs cargo transport in neurons
10-24-2006 · EurekAlert!
Getting molecular cargo from the cell body to the synapse of nerve cells is crucial for learning and memory, even for survival of the cell itself. New research conducted at Brown University and the Marine Biological Laboratory in Woods Hole, Mass., shows that a single peptide can load and direct this biological material. This peptide "ZIP Code" comes from amyloid precursor protein, the principal player in the development of Alzheimer's disease.
Similar news · Read more »
