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Key found to kill cystic fibrosis superbug
04-24-2007 · EurekAlert!Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia. These investigators, under the leadership of Dr. Miguel Valvano, Department of Microbiology and Immunology, have had their research published in the May issue of the Journal of Bacteriology, and highlighted in Nature Reviews/Microbiology.
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Keywords: key, kill, cystic, fibrosis, superbug, fibrosi
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- Peptide discovered in scorpion venom may hold key to secretory diseases
02-14-2008 · EurekAlert!
Researchers have discovered a peptide in scorpion venom that may hold the key to understanding and controlling cystic fibrosis and other secretory diseases. The novel peptide, called GaTx1, can control the movement of ions and water out of cells by interacting with a crucial chloride channel that is commonly mutated in patients with cystic fibrosis.
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- Together we stand: bacteria organize to survive hostile zones
11-13-2007 · EurekAlert!
Using an innovative device, researchers have gleaned important new information about how bacteria survive in hostile environments by forming antibiotic-resistant communities called biofilms. These biofilms play key roles in cystic fibrosis, urinary tract infections and other illnesses.
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- Technology reveals 'lock and key' proteins behind diseases
04-12-2007 · EurekAlert!
A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.
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- Cystic Fibrosis Foundation reports upward trend for key health outcomes
01-28-2008 · EurekAlert!
The Cystic Fibrosis Foundation reported today that key indicators of health for people with cystic fibrosis -- including lung function and nutritional status -- are rising nationwide across its accredited care center network. In fact, the outlook for people with CF continues to improve steadily each year -- and this progress is accelerating due to quality improvement programs spearheaded by the CF Foundation. The National Institutes of Health has recognized the Foundation's care center network as a model for delivering care for a chronic disease.
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- Newly discovered proteins associated with cystic fibrosis
11-03-2006 · EurekAlert!
Researchers have found a highly unusual distribution of proteins in the lungs and airways of people with cystic fibrosis. The discovery is preliminary, but intriguing: Finding out more about the proteins could help sort out the immune system's role in the disease. The study will be presented at a meeting of the American Physiological Society, "Physiological Genomics and Proteomics of Lung Disease," on Nov. 3.
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- High-dose ibuprofen may slow cystic fibrosis lung disease -- especially in children
10-16-2007 · EurekAlert!
This updated Cochrane Review supports the intriguing suggestion that long-term high-dose ibuprofen slows the rate of decline in lung function in children with cystic fibrosis when treatment is started under the age of 13.
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- Chemical chaperone could open door to treatment of neurological disorder
02-05-2008 · EurekAlert!
An unexpected finding turned out to be a clue leading researchers at Washington University School of Medicine in St. Louis to propose a new treatment approach for Niemann-Pick disease, a rare, deadly neurodegenerative disorder. They believe the approach also could be useful for more common diseases -- such as cystic fibrosis -- that stem from a similar type of defect.
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- New designer toxins kill Bt-resistant insect pests
11-01-2007 · EurekAlert!
A new way to combat resistant pests stems from discovering how the widely-used natural insecticide Bt kills insects. Figuring out how Bt toxins punch holes in the cells of an insect's gut was the key to designing the new toxins, according to new research. Some pest insects have developed resistance to Bt toxins, naturally occurring insecticides used worldwide to combat both crop pests and disease-carrying mosquitoes.
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- Proteins may predict lung transplant rejection
11-03-2006 · EurekAlert!
Researchers have identified three proteins that appear to be highly predictive of chronic lung rejection up to 20 months before the rejection occurred. Lung transplants are a common therapy for many end-stage lung diseases such as chronic obstructive pulmonary disease, cystic fibrosis and pulmonary hypertension. If doctors can predict which patients are beginning to reject the transplanted organ, they could try to head it off.
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- JCI table of contents: Oct. 18, 2007
10-18-2007 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Oct. 18, 2007, in the JCI, including: New links in the cystic fibrosis chain uncover potential therapeutics; How one bacteria colonizes the gut and causes food poisoning; When you gotta go, you gotta go: a role for TRPV4 in normal bladder function; IL-15R-alpha takes center stage in one immune response; and others.
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