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New hereditary breast cancer gene discovered

04-25-2007 · EurekAlert!

New hereditary breast cancer gene discovered.

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Keywords: hereditary, breast, cancer, gene, discovered

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  1. Linchpin gene may be useful target for new breast cancer therapies
    09-15-2007 · EurekAlert!
    University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone-responsive breast cancers, and may explain differences in the effectiveness of current treatments.
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  2. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
    10-11-2007 · EurekAlert!
    A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers have discovered that the protein pp32 -- which normally applies the brakes on a cancer-causing gene -- is missing in an aggressive form of pancreatic cancer. Though the work is preliminary, the scientists say, the absent protein could eventually become a marker for the disease and a potential drug target.
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  3. New pathway provides more clues about BRCA1 role in breast cancer
    01-15-2008 · EurekAlert!
    A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer.
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  4. Research linking Ashkenazi Jews & breast cancer genes beset by problems
    11-01-2006 · EurekAlert!
    Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November 2006 issue of the American Journal of Public Health challenges this population-based approach, warning that disparities in access to care and other unintended consequences for specific ethic groups can result, and may have already occurred.
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  5. 'Network' approach identifies potential breast cancer susceptibility gene
    10-09-2007 · EurekAlert!
    Like a crossword-puzzle solver who uses the letters in some answers to figure out others, researchers at Dana-Farber Cancer Institute and an international group of collaborators have used data on genes involved in inherited forms of breast cancer to identify a gene linked to non-hereditary cases of the disease.
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  6. Research linking Ashkenazi Jews and breast cancer genes beset by problems
    11-01-2006 · EurekAlert!
    Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November 2006 issue of the American Journal of Public Health challenges this population-based approach, warning that disparities in access to care and other unintended consequences for specific ethic groups can result, and may have already occurred.
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  7. 'Cancer prognosis gene' found to control the fate of breast cells
    11-30-2006 · EurekAlert!
    Scientists have discovered an unsuspected role for a gene known to be one of the best predictors of human breast cancer outcome.
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  8. New study warns against linking ethnic identity to breast cancer genes
    10-26-2006 · EurekAlert!
    Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November issue of The American Journal of Public Health challenges this approach, warning that disparities in access to care and other unintended consequences can, and have, resulted.
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  9. Colon cancer risk in US traced to common ancester
    01-02-2008 · EurekAlert!
    A married couple who sailed from England to America around 1630 may be the ancestors of hundreds of people alive today who are at risk for a hereditary form of colon cancer. Researchers from Huntsman Cancer Institute at the University of Utah have discovered a mutation that has been traced from many individuals today back to a common ancestor -- which may contribute to a significant percentage of colon cancer cases in the United States.
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  10. Gene markers located for hereditary prostate cancer
    01-16-2008 · EurekAlert!
    Researchers at the Johns Hopkins Brady Urological Institute, Wake Forest University and the Karolinska Institute in Sweden have identified an array of gene markers for hereditary prostate cancer that, along with family history for the disease, appear to raise risk to more than nine times that of men without such markers. The panel, gleaned from a study of more than 4,000 Swedes, found that these markers are common and could account for nearly half of the prostate cancer cases in this study.
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