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Morphine makes lasting -- and surprising -- change in the brain

04-25-2007 · EurekAlert!

Morphine stops the synapse-strengthening process in the brain known as long-term potentiation at inhibitory synapses, according to new research conducted by Brown University brain scientist Julie Kauer. In Nature, Kauer explains this startlingly persistent effect, which could contribute to addiction and may provide a target for treatments of opioid addiction. The research also supports a provocative theory of addiction as a disease of learning and memory.

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