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Anti-fungal drug stops blood vessel growth
04-27-2007 · EurekAlert!Researchers at Johns Hopkins have discovered to their surprise that a drug commonly used to treat toenail fungus can also block angiogenesis, the growth of new blood vessels commonly seen in cancers. The drug, itraconazole, is already FDA approved for human use, which may fast-track its availability as an anti-angiogenesis drug.
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Keywords: anti-fungal, drug, stops, blood, vessel, growth, anti, fungal, stop
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- Blood-vessel blocker aids cancer-killing virus
11-27-2007 · EurekAlert!
Cancer-killing viruses are a promising therapy for incurable brain tumors, but their effectiveness has been limited in part because immune cells rapidly eliminate them. That immune response might be slowed, and the virus given more time to kill cancer cells, by blocking the growth of blood vessels in the tumor, new Ohio State research suggests. The study indicates that pretreatment with a drug that blocks blood-vessel growth might improve the effectiveness of cancer-killing viruses.
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- Protein controls blood vessel formation, offers new drug target
12-04-2007 · EurekAlert!
A protein called CIB1 discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine appears to play a major role in controlling new blood vessel growth, offering a target for drug treatments to help the body repair itself after injury and control unwanted blood vessel growth.
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- New treatment for age-related macular degeneration within sight
11-29-2007 · EurekAlert!
With 8 million people at high risk for advanced age-related macular degeneration, researchers from Harvard and Japan discovered that the experimental drug, endostatin, may be the cure. A research report published in the December 2007 issue of The FASEB Journal, describes how giving endostatin to mice significantly reduced or eliminated abnormal blood vessel growth within the eye, which is ultimately why the disease causes blindness.
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- Study reveals a key to blood vessel growth and possible drug target
10-14-2007 · EurekAlert!
Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and atherosclerosis, the researchers say.
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- New treatment boosts bone healing and regrowth
01-09-2008 · EurekAlert!
A drug originally used to treat iron poisoning can significantly boost the body's ability to heal and regrow injured bones, according to a new study. Bone density following the new treatment more than doubled. Researchers found new blood vessel growth, necessary for bone healing, was achieved through a cell pathway.
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- Chemical in red wine, fruits and vegetables stops cancer, heart disease, depending on the dose
10-30-2007 · EurekAlert!
The next cancer drug might come from the grocery store, according to research published in the November 2007 issue of the FASEB Journal. In the study, scientists describe how high and low doses of polyphenols have different effects. Most notably, they found that very high doses of polyphenols shut down and prevent tumors by stopping the formation of new blood vessels needed for growth. Polyphenols are found in red wine, fruits, vegetables and green tea.
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- Obesity drug helps unlock clues about cancer
02-01-2007 · EurekAlert!
An approved drug for fighting obesity is helping scientists at Wake Forest University School of Medicine uncover clues about how to stop the growth of cancerous tumors.
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- Targeting surgar on blood vessels may inhibit cancer growth
05-07-2007 · EurekAlert!
In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego, School of Medicine have targeted a sugar that supports blood vessel growth in the tumor. Their findings will be published in the May 7 online issue of Journal of Cell Biology.
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- Novel method enables genomic screening of blood vessels from patient tissue
08-28-2007 · EurekAlert!
Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.
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- CSHL scientists successfully target tumor microenvironment to stop cancer growth
06-15-2007 · EurekAlert!
Cold Spring Harbor Laboratory (CSHL) researchers led by Daniel Nolan and Assistant Professor Vivek Mittal have found that bone marrow (BM) derived endothelial progenitor cells (EPCs) play a critical role in the early stages of tumor progression and that eliminating EPCs stops cancer growth.
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