Daily non-political popular news in brief.
Mice with a migraine show signs of brain damage
04-30-2007 · EurekAlert!Migraines may be doing more than causing people skull-splitting pain. Scientists have found evidence that the headaches may also be acting like tiny transient strokes, leaving parts of the brain starved for oxygen and altering the brain in significant ways.
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Keywords: mice, migraine, show, signs, brain, damage, sign
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- Jefferson immunology researchers show blood-brain barrier damage could affect MS severity
04-05-2007 · EurekAlert!
Immunology researchers at the Kimmel Cancer Center at Jefferson studying a multiple sclerosis (MS)-like disease in mice have shown that the amount of "damage" to the central nervous system’s protective blood-brain barrier -- in essence, opening it -- almost always correlates to the severity of the disease. The findings can be used for testing potential MS therapies and for better understanding the role of the blood-brain barrier in disease processes.
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- Cigarette smoke, alcohol damage hearts worse as combo
11-21-2007 · EurekAlert!
A new study shows that taking in smoky air and drinking alcohol basically nullify any potential heart benefit from drinking alcohol by itself. Researchers at the University of Alabama at Birmingham found that mice exposed to smoky air and fed a liquid diet containing ethanol, the intoxicating ingredient in alcohol, had a 4.7-fold increase in artery lesions, a key sign of advancing heart disease. The study appears in Free Radical Biology & Medicine.
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- New risk factors discovered for Alzheimer's disease
07-06-2007 · EurekAlert!
A recent study in Journal of Neuroimaging suggests that cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease. Older adults showing signs of both conditions were seven-times more likely to develop Alzheimer's than their peers.
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- Orexigen: Laboratory studies show Contrave acts on specific brain pathways to reduce food intake
10-23-2007 · EurekAlert!
Laboratory studies show the combination of bupropion and naltrexone (the components of Contrave) acts in a part of the brain where food reward pathways are located and resulted in a 95 percent reduction in food intake in obese mice. This mechanism of action may differentiate Contrave from other obesity therapeutics. Concurrent with these studies, Contrave is in phase 3 clinical trials.
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- VEGF neutralization can damage brain vessels, say Schepens Eye Research Institute scientists
02-12-2008 · EurekAlert!
New research by scientists at Schepens Eye Research Institute may help explain why the anticancer drug Avastin, which targets a growth factor responsible for creation of new blood vessels, causes potentially fatal brain inflammation in certain patients. Institute scientists mimicked the drug's activity in mice and found that it damaged the cell lining that prevents fluid from leaking from the ventricle into the brain.
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- New study finds blood-spinal cord barrier compromised in mice with ALS
11-20-2007 · EurekAlert!
The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis, report researchers at the University of South Florida Center for Aging and Brain Repair. The barrier disruption was found in mice at both early and late stages of ALS, a progressive neurodegenerative disease affecting nerve cells in the brain and the spinal cord. The study appears in the online, open-access journal PLoS ONE.
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- Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
11-29-2006 · EurekAlert!
Drugs used to treat cancer may damage normal, healthy brain cells more than the cancer cells they are meant to target. A study published today in the open access journal Journal of Biology shows that clinical doses of chemotherapeutic drugs used to treat many common cancers cause long-term damage to the brains of mice.
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- Females more prone to brain damage from alcohol abuse
07-25-2007 · EurekAlert!
Alcoholism has traditionally been considered a male disease because there are many more alcoholic males than females. But a study by researchers at Oregon Health & Science University and the Portland Veterans Affairs Medical Center suggests that women are more prone to brain damage from alcohol abuse than men. The study found that female mice are more susceptible to neurotoxic effects of alcohol withdrawal, including significantly increased brain cell death, than male mice.
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- MS that runs in families appears more severe than non-familial MS
10-12-2007 · EurekAlert!
Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.
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- Making mice with enhanced color vision
03-22-2007 · EurekAlert!
Researchers at the Johns Hopkins School of Medicine and their colleagues have found that mice simply expressing a human light receptor in addition to their own can acquire new color vision, a sign that the brain can adapt far more rapidly to new sensory information than anticipated.
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